Advances in Stem Cell Therapy

1. Front Matter

   Pages i-xvi

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2. The Use of Adult Stem Cell Therapy for Selected Diseases

   1. Front Matter

      Pages 1-1

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   2. Hematopoietic Stem Cell Transplantation in Pediatric Diseases

      • Sule Unal, Duygu Uckan-Cetınkaya

      Pages 3-18

   3. Stem Cell Therapy in Diabetes Mellitus

      • Mohamed A. Ghoneim, Ayman F. Refaie

      Pages 19-30

   4. Stem Cell Therapies in Neurological Disorders

      • Fatima Abbas Jamali, Said Salah Dahbour

      Pages 31-59

   5. Stem Cells in Diseases of Aging

      • Ming Li, Susumu Ikehara

      Pages 61-75

   6. Therapeutic Prospects of Stem Cells in Benign Urological Conditions

      • Amjad Alwaal, Tom F. Lue

      Pages 77-93

   7. Clinical Applications of Stem Cells in Women’s Reproductive Health

      • Noha Mousa, Sherif Abdelkarim Shazly, Ahmed Abobakr Nassr

      Pages 95-114

3. Novel Applications of Special Types of Stem Cells

   1. Front Matter

      Pages 115-115

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   2. Adipose-Derived Stem Cell-Based Therapies in Regenerative Medicine

      • Ahmed El-Badawy, Sara M. Ahmed, Nagwa El-Badri

      Pages 117-138

   3. Advances in Umbilical Cord Blood Therapy: Hematopoietic Stem Cell Transplantation and Beyond

      • Theresa Chow, Sue Mueller, Ian M. Rogers

      Pages 139-168

4. Applications of Stem Cells in Tissue Engineering

   1. Front Matter

      Pages 169-169

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   2. Dental Pulp Stem Cells in Tissue Engineering and Regenerative Medicine: Opportunities for Translational Research

      • Rania M. El Backly, Mona K. Marei

      Pages 171-196

   3. Stem Cell Therapy and Tissue Engineering in Urogenital Diseases

      • Ingrid Saba, Sophie Ramsay, Stéphane Bolduc, Hazem Orabi

      Pages 197-223

   4. Stem Cell Therapy for Autoimmune Disease

      • Phuc Van Pham

      Pages 225-248

   5. Treatment of Hepatic Malignances and Disorders: The Role of Liver Bioengineering

      • Pilar Sainz-Arnal, Iris Plá-Palacín, Natalia Sánchez-Romero, Pedro M. Baptista

      Pages 249-276

   6. Advances in Micro- and Nanotechnologies for Stem Cell-Based Translational Applications

      • Jian Chen, Mohamed Y. Elsayed, Yuanchen Wei, Noha Mousa

      Pages 277-302

5. Erratum: Chapter 6 Clinical Applications of Stem Cells in Women’s Reproductive Health

   • Noha Mousa, Sherif Abdelkarim Shazly, Ahmed Abobakr Nassr

   Pages E1-E1

6. Back Matter

   Pages 303-310

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The book reviews the main approaches for generation of differentiated cells from various types of stem cells, including embryonic, placental and cord blood stem cells through marrow, adipose tissue and dental pulp. The book starts with an overview of experimental protocols applied to generate insulin secreting cells, neural cells, heart cells, and other tissue specific cells ex vivo and in experimental animals. This is followed by exhaustive review of clinical trials in these pathologies. It continues with a comparison of the merits of successful transplantation in humans versus animal experimentation, and highlights the most promising clinical applications in the field. Special chapters are devoted to the topic of tissue engineering and modern synthetic and biological scaffolds. It is essential reading for scientists and researchers in tissue engineering and stem cell research as well as clinicians who are involved in developing or testing stem cell therapies.

• cord blood
• hematopoiesis
• insulin
• tissue engineering
• neurodegenerative disease

• Center of Excellence for Stem Cells and Regenerative Medicine, Zewail City of Science and Technology, Zayed City, Egypt

  Nagwa El-Badri

Dr. Nagwa El-Badri is currently Professor and Founding Chair, Biomedical Sciences Programs, at the University of Science and Technology, and and Director of Center of Excellence for Stem Cells and Regenerative Medicine Zewail City of Science and Technology, in Giza, Egypt. She received her MD with Honors at Cairo University and a PhD with distinction from the University of South Florida College of Medicine. She was previously Director, Women’s Health Graduate and Undergraduate Program, University of South Florida College of Medicine. Her research focus areas include stem cell biology, autoimmune diseases, cord blood banking and women's health.

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