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Handbook of HER2-Targeted Agents in Breast Cancer

  • Book
  • © 2016

Overview

Authors:
  1. Ricardo H Alvarez

    1. Cancer Treatment Centers of America, NEWNAN, USA

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  2. Javier Cortés

    1. Institute of Oncology, Passeig Vall d'Hebron, Barcelona, Spain

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  3. Mary Falzon

    1. University College Hospital, London, United Kingdom

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  4. Michael Gandy

    1. Health Service Laboratories, London, United Kingdom

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  5. Luca Gianni

    1. Scientific Institute, Ospedale San Raffaele, Milan, Italy

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  6. Nadia Harbeck

    1. University of Munich, Munich, Germany

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  7. Martine Piccart

    1. Institut Jules Bordet, Brussels, Belgium

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  • Provides a timely and informative overview of the role of HER2 in breast cancer and the implications for treatment
  • Includes evidence-based discussion of major clinical trials and the most recent guidelines for diagnosis and treatment of HER2-positive breast cancer
  • Written by leading experts in the field of breast oncology and histopathology
  • Includes supplementary material: sn.pub/extras

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Table of contents (6 chapters)

  1. Front Matter

    Pages I-XI
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  2. Introduction and background biology

    • Angelica Fasolo, Luca Gianni
    Pages 1-13

  3. HER2 testing

    • Mary Falzon, Michael Gandy
    Pages 15-27

  4. HER2-positive breast cancer: neoadjuvant and adjuvant therapy

    • Nadia Harbeck
    Pages 29-49

  5. HER2-positive metastatic breast cancer: first-line treatment

    • Leticia De Mattos-Arruda, Javier Cortés
    Pages 51-69

  6. HER2-positive metastatic breast cancer: second-line treatment

    • Ricardo H. Alvarez
    Pages 71-86

  7. Emerging targeted agents for HER2-positive breast cancer

    • Dimitrios Zardavas, Martine Piccart
    Pages 87-110
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Keywords

About this book

This concise handbook provides oncologists and other healthcare providers with crucial updates in the field, including an updated review of the current understanding of the biology of the HER2 pathway, an overview of HER2-testing, and evidence-based discussions of available and emerging HER2-targeted treatment options. An essential clinical text for physicians that screen and treat patients with breast cancer and require an accessible, up-to-date survey of the dynamic treatment landscape.

Authors and Affiliations

  • Cancer Treatment Centers of America, NEWNAN, USA

    Ricardo H Alvarez

  • Institute of Oncology, Passeig Vall d'Hebron, Barcelona, Spain

    Javier Cortés

  • University College Hospital, London, United Kingdom

    Mary Falzon

  • Health Service Laboratories, London, United Kingdom

    Michael Gandy

  • Scientific Institute, Ospedale San Raffaele, Milan, Italy

    Luca Gianni

  • University of Munich, Munich, Germany

    Nadia Harbeck

  • Institut Jules Bordet, Brussels, Belgium

    Martine Piccart

About the authors

Ricardo Alvarez is Director of Clinical Research and Breast Cancer Specialist at Cancer Treatment Centers of America in Atlanta, Georgia.
Javier Cortes is Deputy Director of the Breast Cancer Program, Head of the Breast Cancer and Melanoma Group in the Oncology Department of Vall d’Hebron University Hospital in Barcelona, Spain.


Mary Falzon is Consultant histo/cytopathologist and Divisional Clinical Director for University College London Hospitals in London, UK.


Michael Gandy is lead biomedical scientist and clinical services manager at University College London- Advanced Diagnostics in London, UK.


Luca Gianni is the Director of the Department of Medical Oncology at the Hospital San Raffaele in Milan, Italy.


Nadia Harbeck is Head of the Breast Center at the University of Munich and heads the Oncological Therapy and Clinical Trials Unit in Obstetrics and Gynecology in Munich,Germany.


Martine Piccart is Professor of Oncology at the Université Libre de Bruxelles and Director of Medicine at the Jules Bordet Institute, in Brussels, Belgium.

Bibliographic Information

  • Book Title: Handbook of HER2-Targeted Agents in Breast Cancer

  • Authors: Ricardo H Alvarez, Javier Cortés, Mary Falzon, Michael Gandy, Luca Gianni, Nadia Harbeck, Martine Piccart

  • DOI: https://doi.org/10.1007/978-3-319-28216-9

  • Publisher: Adis Cham

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer International Publishing Switzerland 2016

  • Softcover ISBN: 978-3-319-28214-5Published: 27 May 2016

  • eBook ISBN: 978-3-319-28216-9Published: 14 May 2016

  • Edition Number: 2

  • Number of Pages: XI, 110

  • Number of Illustrations: 1 b/w illustrations, 16 illustrations in colour

  • Topics: Oncology, Primary Care Medicine, Diagnostic Radiology

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