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Apoptotic and Non-apoptotic Cell Death

  • Book
  • © 2017

Overview

Editors:
  1. Shigekazu Nagata

    1. Biochemistry & Immunology, WPI Immunology frontier research center, Osaka University, Osaka, Japan

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  2. Hiroyasu Nakano

    1. Department of Biochemistry, Toho University School of Medicine, Tokyo, Japan

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    You can also search for this editor in PubMed   Google Scholar

  • Provides new insights into the mechanisms causing cell death
  • Presents recent studies on various types of non-apoptotic forms of cell death including regulated necrosis, pyroptosis, entosis, and ferroptosis
  • Shows that apoptotic cells release various factors that are involved in inflammation, proliferation, immune tolerance, and tissue repair in a context dependent manner
  • Includes supplementary material: sn.pub/extras

Part of the book series: Current Topics in Microbiology and Immunology (CT MICROBIOLOGY, volume 403)

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Table of contents (7 chapters)

  1. Front Matter

    Pages i-vii
    Download chapter PDF

  2. Prix Fixe: Efferocytosis as a Four-Course Meal

    • Jennifer Martinez
    Pages 1-36

  3. Emerging Roles for RIPK1 and RIPK3 in Pathogen-Induced Cell Death and Host Immunity

    • Danish Saleh, Alexei Degterev
    Pages 37-75

  4. Epithelial Cell Death and Inflammation in Skin

    • Snehlata Kumari, Manolis Pasparakis
    Pages 77-93

  5. IAPs and Cell Death

    • John Silke, James Vince
    Pages 95-117

  6. Cellular FLICE-Inhibitory Protein Regulates Tissue Homeostasis

    • Hiroyasu Nakano, Xuehua Piao, Ryodai Shindo, Sachiko Komazawa-Sakon
    Pages 119-141

  7. Lipid Peroxidation-Dependent Cell Death Regulated by GPx4 and Ferroptosis

    • Hirotaka Imai, Masaki Matsuoka, Takeshi Kumagai, Taro Sakamoto, Tomoko Koumura
    Pages 143-170

  8. Immune Regulation by Dead Cell Clearance

    • Masato Tanaka, Gen Nishitai
    Pages 171-183
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Keywords

About this book

This volume focuses on apoptotic and non-apoptotic programmed cell death, including necroptosis, pyroptosis, and ferroptosis, and presents recent findings in the field. It discusses the crucial role that apoptotic and non-apoptotic cell death play in various pathological conditions, such as skin diseases, inflammatory bowel diseases, and virus infections. Further, it highlights the mechanisms underlying the recognition and clearance of dead cells, and the subsequent biological responses triggered by phagocytosed macrophages and factors released from dying cells.Offering insights into cell death, it is a valuable resource for researchers and clinicians developing novel strategies to treat various diseases that are closely associated with cell death.

Editors and Affiliations

  • Biochemistry & Immunology, WPI Immunology frontier research center, Osaka University, Osaka, Japan

    Shigekazu Nagata

  • Department of Biochemistry, Toho University School of Medicine, Tokyo, Japan

    Hiroyasu Nakano

About the editors

Shigekazu Nagata is a professor of Graduate School of Medicine, Kyoto University, Japan. Hiroyasu Nakano is a professor of Graduate School of Medicine, Toho University, Japan.

Bibliographic Information

  • Book Title: Apoptotic and Non-apoptotic Cell Death

  • Editors: Shigekazu Nagata, Hiroyasu Nakano

  • Series Title: Current Topics in Microbiology and Immunology

  • DOI: https://doi.org/10.1007/978-3-319-23913-2

  • Publisher: Springer Cham

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2017

  • Hardcover ISBN: 978-3-319-23912-5Published: 18 April 2017

  • Softcover ISBN: 978-3-319-79553-9Published: 17 July 2018

  • eBook ISBN: 978-3-319-23913-2Published: 07 April 2017

  • Series ISSN: 0070-217X

  • Series E-ISSN: 2196-9965

  • Edition Number: 1

  • Number of Pages: VII, 183

  • Topics: Immunology

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