Functional Mapping of the Cerebral Cortex

1. Front Matter

   Pages i-xvi

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2. Historical Perspective on the Development of Cerebral Localization, Cerebral Cortical Motor Stimulation, and Sensory Evoked Potentials

   • James L. Stone, Ashley N. Selner, Vimal A. Patel

   Pages 1-21

3. Anatomy of Important Functioning Cortex

   • Warren Boling, André Olivier

   Pages 23-40

4. Mapping Eloquent Brain with Functional MRI and DTI

   • Mohammad Fakhri, Lauren J. O’Donnell, Laura Rigolo, Alexandra J. Golby

   Pages 41-62

5. Intraoperative Cortical Mapping Techniques and Limitations

   • Juanita M. Celix, Daniel L. Silbergeld

   Pages 63-76

6. Anesthetic Considerations in Cortical Mapping and Awake Surgery

   • Lee A. Tan, Richard W. Byrne, Mary K. Sturaitis

   Pages 77-90

7. Mapping Cortical Function with Event-Related Electrocorticography

   • Vernon L. Towle, Zhongtian Dai, Weili Zheng, Naoum P. Issa

   Pages 91-104

8. Mapping of Eloquent Cortex in Focal Epilepsy with Intracranial Electrodes

   • Andres M. Kanner, Maria Cristina Alarcon Morcillo

   Pages 105-113

9. Somatosensory- and Motor-Evoked Potentials in Surgery of Eloquent Cortex Under General Anesthesia: Advantages and Limitations

   • Ashley N. Selner, James L. Stone

   Pages 115-139

10. Cortical Mapping with Transcranial Magnetic Stimulation

    • Phiroz E. Tarapore

    Pages 141-157

11. Practical Application of Preoperative and Intraoperative Cortical Mapping in Surgery

    • Sepehr Sani, Carter S. Gerard, Richard W. Byrne

    Pages 159-170

12. Epilepsy Surgery in Eloquent Cortex

    • Carter S. Gerard, Lee A. Tan, Guy M. McKhann, Richard W. Byrne

    Pages 171-179

13. White Matter Tracts

    • Timothy D. Miller Jr., Jordan M. Komisarow, Allan H. Friedman

    Pages 181-208

14. Intraoperative Cortical Stimulation and the Value of Negative Mapping

    • Nader Sanai, Mitchel S. Berger

    Pages 209-218

15. Back Matter

    Pages 219-229

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This book provides up-to-date, practical information on functional mapping in order to assist neurosurgeons responsible for safely removing lesions in and around eloquent cortex – one of the greatest challenges in neurosurgery.  The roles of pre- and intraoperative mapping techniques are clearly explained, highlighting the advantages and limitations of each tool available to the neurosurgeon. The inclusion of treatment algorithms for applications in specific clinical circumstances ensures that the book will serve as a clear guide to this most complex of neurosurgical problems. To further assist the reader, instructive clinical case examples, accompanied by intraoperative photos and other illustrative material, help to explain the applications of functional mapping of eloquent cortex in different pathologies. Practitioners will find the book to be a ready guide to navigation of the practical decisions commonly faced when operating in eloquent cortex.

• Brain Mapping
• Cortical Mapping
• Cortical Stimulation
• Functional Cortex
• Functional Imaging

“This is a monograph describing the history and evolution of modern mapping of the cerebral cortex primarily for clinical neurosurgeons. … I recommend this book to neurosurgeons specializing in cranial procedures. … This book has a purpose for surgeons, residents, fellows, and students with an interest in cranial physiology and surgery.” (Joseph J. Grenier, Amazon.com, January, 2016)

• Department of Neurosurgery, Rush University Medical Center, Chicago, USA

  Richard W. Byrne

Richard William Byrne, MD, has been Professor of Neurosurgery at Rush Medical College, Chicago, Ill., since 2008 and in 2013 was appointed The Roger C. Bone, MD, Presidential Professor of Rush University. He is Medical Director of Rush University Neurosurgery and Chairman of the Department of Neurosurgery at Rush Medical College. Dr. Byrne is certified by the American Board of Neurological Surgery. He has served as an officer in various medical societies and on national committees and is a member of the Board of Directors of the CNS Foundation. Since 2012 he has been Treasurer and Executive Committee member of the Neurosurgical Society of America. In 2014 he received the Gary Lichtenstein Humanitarian Award from Voices Against Brain Cancer. Dr. Byrne has conducted extensive research on diverse topics and is the author of more than 80 articles in peer-reviewed journals as well as over 20 book chapters. He is a member of the editorial board for Surgical Neurology International anduntil 2013 was a member of the editorial board of AANS Neurosurgeon. In 2014 he was a guest editor for Seminars in Oncology, and he is also a reviewer for many other journals.

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