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Natural Compounds as Therapeutic Agents for Amyloidogenic Diseases

  • Book
  • © 2015

Overview

  • Discusses different kinds of studies: biophysics, biochemistry, animal, epidemiological
  • Covers Mediterranean diet and Chinese Traditional Medicine
  • Is a resource for scientists, health professionals and industrialists, providing both basic and specialized information
  • Gives a thorough and in-depth overview
  • State-of-the-art contents with numerous tables and illustrations

Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 863)

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Table of contents (7 chapters)

Keywords

About this book

This edited volume concerns a group of devastating neurological disorders that share a common pathological mechanism, namely the aggregation and deposition of insoluble, proteinaceous lesions, termed ‘amyloid’. Examples of cerebral amyloid disorders include common neurodegenerative diseases like Alzheimer’s disease-related dementia and Parkinson’s disease, as well as other less prevalent conditions like Huntington’s disease, cerebral amyloid angiopathy and the transmissible prion disorders. A disease-modifying therapeutic agent is still lacking for all these diseases, and there are no approved therapies that target amyloid formation directly. Nevertheless, a large and complex group of natural aromatic compounds known as polyphenols are rapidly emerging as potentially potent anti-amyloidogenic agents.

This book collectively presents a considerable body of experimental and epidemiological evidence from peer-reviewed scientific publications that support a role for natural compounds and herbal extracts in the chemoprevention and therapy of amyloidogenic disorders.

Each contribution is written by scientific experts in the relevant field; chapters are devoted to Mediterranean diet and olive oil phenols, traditional Chinese medicine, herbal extracts, polyphenols (with a particular emphasis on epigallocatechin-3-gallate) and bi-flavonoids, amongst others.

The topic of this book is relevant to a wide audience, from academia and university students in the biological and chemical sciences, to physicians and allied health professionals, as well as people working in the nutraceutical industry.

Editors and Affiliations

  • Department of Physiology and Biochemistry, University of Malta, Msida, Malta

    Neville Vassallo

Bibliographic Information

  • Book Title: Natural Compounds as Therapeutic Agents for Amyloidogenic Diseases

  • Editors: Neville Vassallo

  • Series Title: Advances in Experimental Medicine and Biology

  • DOI: https://doi.org/10.1007/978-3-319-18365-7

  • Publisher: Springer Cham

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2015

  • Hardcover ISBN: 978-3-319-18364-0Published: 01 July 2015

  • Softcover ISBN: 978-3-319-35950-2Published: 15 October 2016

  • eBook ISBN: 978-3-319-18365-7Published: 19 June 2015

  • Series ISSN: 0065-2598

  • Series E-ISSN: 2214-8019

  • Edition Number: 1

  • Number of Pages: VII, 163

  • Number of Illustrations: 15 b/w illustrations, 26 illustrations in colour

  • Topics: Neurochemistry, Nutrition, Neurology, Pharmacy

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