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The Molecular Biology of Down Syndrome

  • Conference proceedings
  • © 1999

Overview

Editors:
  1. G. Lubec

    1. Universitäts-Kinderklinik, Wien, Österreich

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Part of the book series: Journal of Neural Transmission. Supplementa (NEURAL SUPPL, volume 57)

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Table of contents (25 papers)

  1. Front Matter

    Pages I-X
    Download chapter PDF

  2. Molecular abnormalities of the brain in Down Syndrome: relevance to Alzheimer’s neurodegeneration

    • S. M. de la Monte
    Pages 1-19

  3. Reduced aldehyde dehydrogenase levels in the brain of patients with Down Syndrome

    • G. Lubec, O. Labudova, N. Cairns, P. Berndt, H. Langen, M. Fountoulakis
    Pages 21-40

  4. The Down Syndrome critical region

    • B. L. Shapiro
    Pages 41-60

  5. Neuropathology

    • N. J. Cairns
    Pages 61-74

  6. c-fos expression in brains of patients with Down Syndrome

    • S. Greber-Platzer, B. Balcz, N. Cairns, G. Lubec
    Pages 75-85

  7. Neuronal cell death in Down’s syndrome

    • A. Sawa
    Pages 87-97

  8. Altered gene expression in fetal Down Syndrome brain as revealed by the gene hunting technique of subtractive hybridization

    • E. Kitzmueller, O. Labudova, H. Rink, N. Cairns, G. Lubec
    Pages 99-124

  9. Gene expression in fetal Down Syndrome brain as revealed by subtractive hybridization

    • O. Labudova, E. Kitzmueller, H. Rink, N. Cairns, G. Lubec
    Pages 125-136

  10. Molecular misreading of genes in Down syndrome as a model for the Alzheimer type of neurodegeneration

    • F. W. van Leeuwen, E. M. Hol
    Pages 137-159

  11. Expression of the dihydropyrimidinase related protein 2 (DRP-2) in Down Syndrome and Alzheimer’s disease brain is downregulated at the mRNA and dysregulated at the protein level

    • G. Lubec, M. Nonaka, K. Krapfenbauer, M. Gratzer, N. Cairns, M. Fountoulakis
    Pages 161-177

  12. Gene expression relevant to Down Syndrome: problems and approaches

    • F. Tassone, R. Lucas, D. Slavov, V. Kavsan, L. Crnic, K. Gardiner
    Pages 179-195

  13. Isolation and analysis of chromosome 21 genes potentially involved in Down Syndrome

    • P. Gosset, G. Ait-Ghezala, P.-M. Sinet, N. Créau
    Pages 197-209

  14. Differential display reveals deteriorated mRNA levels of NADH3 (complex I) in cerebellum of patients with Down Syndrome

    • K. Krapfenbauer, B. Chul Yoo, N. Cairns, G. Lubec
    Pages 211-220

  15. Serotonin (5-HT) in brains of adult patients with Down Syndrome

    • R. Seidl, S. T. Kaehler, H. Prast, N. Singewald, N. Cairns, M. Gratzer et al.
    Pages 221-232

  16. Mechanisms of neuronal death in Down’s syndrome

    • Zs. Nagy
    Pages 233-245

  17. Impaired brain glucose metabolism in patients with Down Syndrome

    • O. Labudova, N. Cairns, E. Kitzmüller, G. Lubec
    Pages 247-256

  18. Oxidative stress and neural dysfunction in Down Syndrome

    • R. C. Iannello, P. J. Crack, J. B. de Haan, I. Kola
    Pages 257-267

  19. Expression of the transcription factor ETS2 in brain of patients with Down Syndrome—evidence against the overexpression-gene dosage hypothesis

    • S. Greber-Platzer, D. Schatzmann-Turhani, N. Cairns, B. Balcz, G. Lubec
    Pages 269-281

  20. Neuronal apoptosis inhibitory protein (NAIP)-like immunoreactivity in brains of adult patients with Down syndrome

    • R. Seidl, M. Bajo, K. Böhm, E. C. LaCasse, A. E. MacKenzie, N. Cairns et al.
    Pages 283-291
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Keywords

Editors and Affiliations

  • Universitäts-Kinderklinik, Wien, Österreich

    G. Lubec

Bibliographic Information

  • Book Title: The Molecular Biology of Down Syndrome

  • Editors: G. Lubec

  • Series Title: Journal of Neural Transmission. Supplementa

  • DOI: https://doi.org/10.1007/978-3-7091-6380-1

  • Publisher: Springer Vienna

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer-Verlag Wien 1999

  • Hardcover ISBN: 978-3-211-83378-0Published: 02 December 1999

  • Softcover ISBN: 978-3-211-83377-3Published: 02 December 1999

  • eBook ISBN: 978-3-7091-6380-1Published: 01 December 2013

  • Series ISSN: 0303-6995

  • Edition Number: 1

  • Number of Pages: X, 366

  • Additional Information: Special edition of Journal of Neural Transmission, Suppl. 57

  • Topics: Neurosciences, Molecular Medicine, Human Genetics, Pediatrics, Pathology, Psychiatry

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