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Progress in Drug Research

  • Book
  • © 2000

Overview

Editors:
  1. Ernst Jucker

    1. Ettingen, Switzerland

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  • WELL-ESTABLISHED BOOK SERIES CONTAINING REVIEWS
  • ON A WIDE SPECTRUM OF HIGHLY TOPICAL AREAS IN CURRENT PHARMACEUTICAL AND PHARMACOLOGICAL RESEARCH

Part of the book series: Progress in Drug Research (PDR, volume 55)

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Table of contents (7 chapters)

  1. Front Matter

    Pages i-viii
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  2. Recent advances in prevention and treatment of hepatitis C virus infections

    • Q. May Wang, Beverly A. Heinz
    Pages 1-32

  3. The effects of morphine on cell proliferation

    • Jay A. Glasel
    Pages 33-80

  4. Glucosamine and chondroitin sulfates in the treatment of osteoarthritis: a survey

    • Gerlie C. de los Reyes, Robert T. Koda, Eric J. Lien
    Pages 81-103

  5. Multi-dimensional QSAR in drug research

    • Angelo Vedani, Max Dobler
    Pages 105-135

  6. NMR spectroscopy in drug discovery: Tools for combinatorial chemistry, natural products, and metabolism research

    • Paul A. Keifer
    Pages 137-211

  7. Prostate cancer and the androgen receptor: Strategies for the development of novel therapeutics

    • Laurane G. Mendelsohn
    Pages 213-233

  8. Quantitative structure - activity relationships of cardiotonic agents

    • Satya P. Gupta
    Pages 235-282

  9. Back Matter

    Pages 283-336
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Keywords

About this book

Hepatitis C virus (HCV) was first identified in 1989 as the etiologic agent of non-A, non-B hepatitis [1] and is currently recognized as the leading cause of chronic liver disease worldwide. In contrast to hepatitis B virus infection, in which only about 5% of adult infections become chronic, more than 80% of HCV-infected patients develop chronic hepatitis. Moreover, 20-50% of those persistently infected with HCV will develop liver cirrhosis and hepatocellu­ lar carcinoma (HCC) [2]. It is estimated that there are 10,000 deaths in the USA per year due to chronic liver failure or HCC [3]. In addition, HCV dis­ 25-50% of all liver transplants in US centers, and the ease is responsible for recurrence of HCV infection following liver transplantation is universal [4]. Typically, HCV disease emerges after a 10-20 year period during which symp­ toms, if they exist at all, are mild and non-specific. Although the prevalence varies greatly among different countries, it has been estimated that up to 170 million people (3% of the world's population), are infected with HCV [5]. A recent study in the USA found that 65% of all HCV-infected persons are 30 to 49 years old [6].

Editors and Affiliations

  • Ettingen, Switzerland

    Ernst Jucker

Bibliographic Information

  • Book Title: Progress in Drug Research

  • Editors: Ernst Jucker

  • Series Title: Progress in Drug Research

  • DOI: https://doi.org/10.1007/978-3-0348-8385-6

  • Publisher: Birkhäuser Basel

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer Basel AG 2000

  • Hardcover ISBN: 978-3-7643-6193-8Published: 01 November 2000

  • Softcover ISBN: 978-3-0348-9544-6Published: 30 October 2012

  • eBook ISBN: 978-3-0348-8385-6Published: 06 December 2012

  • Series ISSN: 0071-786X

  • Series E-ISSN: 2297-4555

  • Edition Number: 1

  • Number of Pages: VIII, 336

  • Topics: Medicine/Public Health, general

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