Inflammatory and Infectious Basis of Atherosclerosis

1. Front Matter

   Pages i-xii

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2. Atherosclerosis: an Inflammatory Disease

   • Gerd Schmitz, Michael Torzewski

   Pages 1-21

3. Inflammation in coronary atherosclerosis - pathological aspects

   • Renu Virmani, Frank D. Kolodgie, Allen P. Burke, Andrew Farb

   Pages 23-46

4. Pathology of acute coronary syndromes

   • Allard C. van der Wal, Onno J. de Boer, Anton E. Becker

   Pages 47-59

5. Transplantation-associated arteriosclerosis and inflammation

   • Dani S. Zander

   Pages 61-78

6. Free radicals as mediators of inflammation in atherosclerosis

   • Heraldo P. Souza, Jay L. Zweier

   Pages 79-92

7. Myocardial reperfusion: A State of Inflammation

   • Keith A. Youker, Nikolaos Frangogiannis, Mark L. Entman

   Pages 93-101

8. LOX-1, a potential inflammatory mediator in atherosclerosis

   • Mingyi Chen, Tatsuya Sawamura

   Pages 103-111

9. Angiotensin II as a Mediator of Inflammation in Atherosclerosis

   • M. Ian Phillips, Shuntaro Kagiyama, Hongjiang Chen, Jay L. Mehta

   Pages 113-127

10. Role of Interleukins in Relation to the Renin-Angiotensinsystem in Atherosclerosis

    • Bernhard Schieffer, Helmut Drexler

    Pages 129-140

11. Heme Oxygenase-1, Inflammation and Atherosclerosis

    • Anupam Agarwal, Nathalie Hill-Kapturczak, Harry S. Nick

    Pages 141-158

12. Lymphocyte Activation in Acute Coronary Syndromes

    • Stefano De Servi, Antonino Mazzone

    Pages 159-184

13. Role of Infection in Atherosclerosis and Precipitation of Acute Cardiac Events

    • Francesco Romeo, Fabrizio Clementi, Tom Saldeen, Jay L. Mehta

    Pages 185-201

14. C-reactive Protein — a Prognostic Marker of Inflammation in Atherothrombosis

    • David A. Morrow, Paul M. Ridker

    Pages 203-220

15. Inflammation as a Marker of Outcome in Myocardial Ischemia

    • Luigi M. Biasucci, Dominick J. Angiolillo, Giovanna Liuzzo

    Pages 221-235

16. Antibiotics in the prevention of coronary heart disease: review of the randomised trials

    • John Danesh, Rory Collins

    Pages 237-242

17. Fish Oil — a Potential Therapy for Inflammatory Atherosclerosis

    • Tom Saldeen, Jay L. Mehta

    Pages 243-257

18. Back Matter

    Pages 259-263

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In the last ten years, major strides have been made in defining the presence and role of inflammation in atherosclerosis as well as in injury to the tissues that occurs after episodes of ischemia and reperfusion. In sixteen chapters, written by world-renowned individuals from different countries, the role of inflammation and different mediators in the pathogenesis of atherosclerosis is presented. The significance of inflammation and possible therapeutic implications is also described in depth. This book is of great interest for a wide range of physicians, researchers, and scientists who may want to study more and develop the concept of inflammation and atherosclerosis.

• Angiotensin II
• Renin-Angiotensin-System
• antibiotics
• atherosclerosis
• heart
• infection
• infectious
• pathogenesis
• protein
• tissue
• transplantation
• infectious diseases

• Division of Cardiovascular Disease, University of Arkansas for Medical Sciences, Little Rock, USA

  Jay L. Mehta

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