Overview
- Includes supplementary material: sn.pub/extras
Part of the book series: Progress in Inflammation Research (PIR)
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Table of contents (14 chapters)
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Peripheral consequences of nerve injury
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Spinal cord plasticity following peripheral nerve injury
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Neuropathic pain: preclinical and clinical paradigms
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New treatment strategies for neuropathic pain
Keywords
About this book
Numerous improvements in our understanding of the mechanisms that underlie neuropathic pain states have come from the development of animal models, most of which involve partial peripheral nerve injury. The animal models have shown that nerve injury initiates a cascade of events resulting in altered neurochemistry and molecular biology of the peripheral neurons, the dorsal root ganglion cell, and changes in neurotransmitter and receptor expression in the dorsal horn of the spinal cord. Moreover, nerve injury produces anatomical changes with functional consequences.
This volume summarises the current understanding of the pathophysiological processes in the peripheral and central nervous system that contribute to the neuropathic pain. It provides a timely review of neuropathic pain mechanisms, written by experts in the field.
Editors and Affiliations
Bibliographic Information
Book Title: Mechanisms and Mediators of Neuropathic Pain
Editors: Annika B. Malmberg, Sandra R. Chaplan
Series Title: Progress in Inflammation Research
DOI: https://doi.org/10.1007/978-3-0348-8129-6
Publisher: Birkhäuser Basel
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eBook Packages: Springer Book Archive
Copyright Information: Birkhäuser Verlag 2002
Hardcover ISBN: 978-3-7643-6237-9Published: 01 April 2002
Softcover ISBN: 978-3-0348-9448-7Published: 21 October 2012
eBook ISBN: 978-3-0348-8129-6Published: 06 December 2012
Series ISSN: 1422-7746
Series E-ISSN: 2296-4525
Edition Number: 1
Number of Pages: XII, 260
Topics: Immunology, Neurosciences, Pain Medicine, Life Sciences, general