Heat Shock Proteins and Inflammation

1. Front Matter

   Pages i-xiii

   PDF

2. HSP60 and the regulation of inflammation: Physiological and pathological

   • Irun R. Cohen, Francisco J. Quintana, Gabriel Nussbaum, Michal Cohen, Alexandra ZaninZhorov, Ofer Lider

   Pages 1-13

3. Heat shock proteins and suppression of inflammation

   • Willem van Eden, Liesbeth Paul, Ruurd van der Zee

   Pages 15-31

4. Heat shock proteins in immune response

   • Sreyashi Basu, Pramod Srivastava

   Pages 33-42

5. Heat shock protein-mediated activation of innate immune cells

   • Clarissa U. I. Prazeres da Costa, Hermann Wagner, Thomas C. Miethke

   Pages 43-54

6. Eukaryotic HSP60: A “danger signal” for T- and natural killer cells

   • Arne van Bonin, Minka Breloer, Solveig H. Moré

   Pages 55-67

7. Heat shock proteins and experimental arthritis

   • Rebecca J. Brownlie, Stephen J. Thompson

   Pages 69-82

8. Heat shock proteins and reactive arthritis

   • J. S. Hill Gaston, Richard C. Duggleby, Jane C. Goodall, Roberto Raggiaschi, Mark S. Lillicrap

   Pages 83-96

9. The development of immune therapy with HSP60 for juvenile idiopathic arthritis

   • Ismé M. de Kleer, Berent P. Prakken, Salvatore Albani, Wietse Kuis

   Pages 97-108

10. Heat shock proteins and rheumatoid arthritis

    • Gabriel S. Panayi, Valerie M. Corrigall

    Pages 109-137

11. Heat shock proteins for immunotherapy of rheumatoid arthritis

    • Gisella L. Puga Yung, Tho D. Le, Sarah Roord, Berent Prakken, Salvatore Albani

    Pages 139-158

12. Immunity to heat shock proteins and atherosclerosis

    • Michael Knoflach, Bruno Mayrl, Mahavir Singh, Georg Wick

    Pages 159-173

13. Chaperonins: Chameleon proteins that influence myeloid cells

    • Brian Henderson

    Pages 175-192

14. Heat shock protein receptors, functions and their effect on monocytes and dendritic cells

    • Thomas Lehner, Yufei Wang, Charles Kelly

    Pages 193-216

15. Heat shock protein expression in transplanted kidney

    • Klemens Trieb

    Pages 217-231

16. Mycobacterial heat shock proteins and the bovine immune system

    • Ad P Koets

    Pages 233-244

17. Microbial infection generates pro-inflammatory autoimmunity against the small heat shock protein alpha B-crystallin and provides the fuel for the development of multiple sclerosis

    • Johannes M. van Noort

    Pages 245-256

18. HSP60-peptide interference with CD94/NKG2 receptors

    • Kalle Söderström

    Pages 257-272

19. Back Matter

    Pages 273-280

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Heat shock proteins (HSP) have received ample interest by immunologists over recent years. Initially they were found to be dominantly immunogenic microbial antigens. The connection with inflammation was established when it was uncovered that T cells specific for these antigens have a crucial role in the induction and regulation of experimental arthritis. Since then, the raised presence of immunity to HSPs in virtually all conditions of inflammation, including autoimmune diseases, transplant rejection and atherosclerosis, has emphasised the critical significance of immunity to HSPs in inflammatory diseases.

• Activation
• Arthritis
• bacteria
• diseases
• immune response
• immune system
• immunity
• immunotherapy
• inflammation
• influence
• kidney
• mycobacteria
• proteins
• regulation
• rheumatoid arthritis

• Division of Immunology, Department of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, University of Utrecht, Utrecht, The Netherlands

  Willem Eden

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