Overview
- Comprehensive review of the clinical and experimental aspects of IL-17, IL-22 and their producing cells
- Completely revised 2nd edition, including additional chapters on the IL-17 receptor family and signaling, or on IL-22 and innate lymphoid cells
- Latest clinical progress in neutralizing IL-17 antibodies
- Includes supplementary material: sn.pub/extras
Part of the book series: Progress in Inflammation Research (PIR)
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Table of contents (24 chapters)
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Front Matter
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Discovery and Basic Aspects of IL-17
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Front Matter
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Discovery and basic aspects of IL-17
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Experimental Models of Disease
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Front Matter
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Experimental models of disease
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Role of IL-23-1 L-17 in Infection and Tumor Control
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Front Matter
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Role of IL-23-1L-17 in infection and tumor control
Keywords
About this book
The knowledge of Th17 cells and other cell populations which secrete IL-17A, and/or IL-22 has expanded tremendously since the publication of the first edition “Th17 Cells: Role in Inflammation and Autoimmune Disease” in 2008. The present volume has been completely revised with the addition of new chapters on the IL-17 receptor family and signaling, and an in-depth review of IL-22 and innate lymphoid cells. The differentiation of naïve T cells into regulatory T cells and Th17 cells as well as the plasticity of Th17 cells is discussed. The role of IL-22 in cutaneous inflammation including psoriasis has been reviewed. In addition, the volume contains critical updates on autoimmunity, organ transplantation, tumor immunology and genetic mouse models for mechanistic studies. Lastly, the latest clinical progress in neutralizing antibodies to IL-17A, IL-17RA not only confirms the therapeutic promise foreseen in 2008, but also improves our knowledge of the pathogenesis of autoimmune diseases. In summary, this is a timely update and important review of the clinical and experimental aspects of IL-17, IL-22 and their producing cells.
Editors and Affiliations
Bibliographic Information
Book Title: IL-17, IL-22 and Their Producing Cells: Role in Inflammation and Autoimmunity
Editors: Valérie Quesniaux, Bernhard Ryffel, Franco Padova
Series Title: Progress in Inflammation Research
DOI: https://doi.org/10.1007/978-3-0348-0522-3
Publisher: Springer Basel
eBook Packages: Medicine, Medicine (R0)
Copyright Information: Springer Basel 2013
Hardcover ISBN: 978-3-0348-0521-6Published: 14 December 2012
Softcover ISBN: 978-3-0348-0773-9Published: 29 January 2015
eBook ISBN: 978-3-0348-0522-3Published: 13 December 2012
Series ISSN: 1422-7746
Series E-ISSN: 2296-4525
Edition Number: 2
Number of Pages: X, 354
Additional Information: 2nd revised edition
Topics: Immunology, Cytokines and Growth Factors, Receptors, Cell Biology, Infectious Diseases, Cancer Research