Overview
- Shares new insights into how fungal pathogens damage host cells
- Covers key aspects of fungal pathogenesis and the mechanisms behind fungal virulence
- Sheds new light on the high costs of, and elevated levels of toxicity in, antifungal therapy
Part of the book series: Current Topics in Microbiology and Immunology (CT MICROBIOLOGY, volume 422)
Access this book
Tax calculation will be finalised at checkout
Other ways to access
Table of contents (10 chapters)
-
Front Matter
Keywords
About this book
This volume offers an overview of the various aspects involved in the ability of fungi to damage host cells, and discusses cutting-edge approaches to the study of fungal pathogenesis. The first chapter illustrate the key roles of glycans and pigments, the most abundant surface components in fungal cells, in their interactions with host cells. The connections between cellular physiology and fungal pathogenesis are then discussed in the following chapters. Physiology-related processes affecting pathogenesis include fungal secretion, morphological transitions, and response to light.
In turn, the book illustrates mechanisms of damage to host cells using the Histoplasma capsulatum model of infection, and reviews the use of transcriptomic approaches to understand the mechanisms of interaction between fungal cells and host tissues. After a discussion of the immunological mechanisms underlying host susceptibility to fungal infections, the book’s closing contribution reviews the mechanisms of interaction between fungi and other microbes, and the impact of this association on fungal pathogenesis. Given its scope, the book will appeal to scientists in the fields of mycology, microbiology, infectious diseases, biology and medicine.
Editors and Affiliations
About the editor
Bibliographic Information
Book Title: Fungal Physiology and Immunopathogenesis
Editors: Marcio L. Rodrigues
Series Title: Current Topics in Microbiology and Immunology
DOI: https://doi.org/10.1007/978-3-030-30237-5
Publisher: Springer Cham
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer Nature Switzerland AG 2019
Hardcover ISBN: 978-3-030-30236-8Published: 19 September 2019
Softcover ISBN: 978-3-030-30239-9Published: 19 September 2020
eBook ISBN: 978-3-030-30237-5Published: 03 September 2019
Series ISSN: 0070-217X
Series E-ISSN: 2196-9965
Edition Number: 1
Number of Pages: VIII, 301
Number of Illustrations: 4 b/w illustrations, 19 illustrations in colour
Topics: Immunology, Medical Microbiology, Pharmacology/Toxicology, Virology