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  • © 2019

Hepatocellular Carcinoma

Translational Precision Medicine Approaches

Editors:

  • Provides a new strategy to advance the clinical care of patients.
  • Provides a comprehensive overview of HCC diagnosis, treatment, and prevention.
  • Written by experts in the field.

Part of the book series: Molecular and Translational Medicine (MOLEMED)

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Table of contents (17 chapters)

  1. Front Matter

    Pages i-xv
  2. Clinical Demographics and Management

    1. Front Matter

      Pages 1-1
    2. Risk Factors of Hepatocellular Carcinoma for Precision Personalized Care

      • Naoto Fujiwara, Po-Hong Liu, Sai Krishna Athuluri-Divakar, Shijia Zhu, Yujin Hoshida
      Pages 3-25
    3. Hepatocellular Carcinoma Surveillance and Staging

      • Amit G. Singal, Neehar D. Parikh, Nicole E. Rich, Binu V. John, Anjana Pillai
      Pages 27-51
    4. Changing Epidemiology of Hepatocellular Carcinoma and Role of Surveillance

      • Yueran Zhuo, Qiushi Chen, Jagpreet Chhatwal
      Pages 53-67
  3. Diagnosis and Prognostication

    1. Front Matter

      Pages 69-69
    2. Radiological Diagnosis and Characterization of HCC

      • Naik Vietti Violi, Sara Lewis, Stefanie Hectors, Daniela Said, Bachir Taouli
      Pages 71-92
    3. Analysis of Hepatocellular Carcinoma Tissue for Biomarker Discovery

      • Connor A. West, Alyson P. Black, Anand S. Mehta
      Pages 93-107
    4. Liquid Biopsy in Hepatocellular Carcinoma

      • Irun Bhan, Daniel A. Haber, Raymond T. Chung, David T. Ting
      Pages 125-141
  4. Treatment

    1. Front Matter

      Pages 143-143
    2. Surgical Therapies in Hepatocellular Carcinoma

      • Caitlin A. Hester, Adam C. Yopp
      Pages 145-167
    3. Interventional Radiologic Therapies for Hepatocellular Carcinoma: From Where We Began to Where We Are Going

      • Patrick D. Sutphin, Daniel Lamus, Sanjeeva P. Kalva, Junjie Li, Ian R. Corbin
      Pages 169-194
    4. Molecular-Targeted Therapies in Hepatocellular Carcinoma

      • Amit Mahipal, Anuhya Kommalapati, Rutika Mehta, Richard D. Kim
      Pages 225-238
    5. Immune Therapies

      • Zachary J. Brown, Tim F. Greten
      Pages 239-253
    6. Prevention Strategies for Hepatocellular Carcinoma

      • Derek J. Erstad, Allen A. Razavi, Shen Li, Kenneth K. Tanabe, Bryan C. Fuchs
      Pages 255-289
  5. Molecular Pathogenesis and Therapeutic Discovery

    1. Front Matter

      Pages 291-291
    2. Stromal and Immune Drivers of Hepatocarcinogenesis

      • Antonio Saviano, Natascha Roehlen, Alessia Virzì, Armando Andres Roca Suarez, Yujin Hoshida, Joachim Lupberger et al.
      Pages 317-331

About this book

This book provides a comprehensive overview of the current limitations and unmet needs in Hepatocellular Carcinoma (HCC) diagnosis, treatment, and prevention. It also provides newly emerging concepts, approaches, and technologies to address challenges. Topics covered include changing landscape of HCC etiologies in association with health disparities, framework of clinical management algorithm, new and experimental modalities of HCC diagnosis and prognostication, multidisciplinary treatment options including rapidly evolving molecular targeted therapies and immune therapies, multi-omics molecular characterization, and clinically relevant experimental models. The book is intended to assist collaboration between the diverse disciplines and facilitate forward and reverse translation between basic and clinical research by providing a comprehensive overview of relevant areas, covering epidemiological trend and population-level patient management strategies, new diagnostic and prognostic tools, recent advances in the standard care and novel therapeutic approaches, and new concepts in pathogenesis and experimental approaches and tools, by experts and opinion leaders in their respective fields.

By thoroughly and concisely covering whole aspects of HCC care, Hepatocellular Carcinoma serves as a valuable reference for multidisciplinary readers, and promotes the development of personalized precision care strategies that lead to substantial improvement of disease burden and patient prognosis in HCC.

Editors and Affiliations

  • Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, USA

    Yujin Hoshida

About the editor

Yujin Hoshida
University of Texas Southwestern Medical Center
Dallas, TX
USA

Bibliographic Information

  • Book Title: Hepatocellular Carcinoma

  • Book Subtitle: Translational Precision Medicine Approaches

  • Editors: Yujin Hoshida

  • Series Title: Molecular and Translational Medicine

  • DOI: https://doi.org/10.1007/978-3-030-21540-8

  • Publisher: Humana Cham

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer Nature Switzerland AG 2019

  • Hardcover ISBN: 978-3-030-21539-2Published: 20 August 2019

  • Softcover ISBN: 978-3-030-21542-2Published: 20 August 2020

  • eBook ISBN: 978-3-030-21540-8Published: 05 August 2019

  • Series ISSN: 2197-7852

  • Series E-ISSN: 2197-7860

  • Edition Number: 1

  • Number of Pages: XV, 364

  • Number of Illustrations: 19 b/w illustrations, 37 illustrations in colour

  • Topics: Pathology, Oncology, Gastroenterology, Hepatology

Buy it now

Buying options

eBook USD 79.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 99.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 109.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access