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  • © 2019

Molecular and Cell Biology of Cancer

When Cells Break the Rules and Hijack Their Own Planet

  • An updated perspective on cancer with a Development and Evolutionary perspective
  • Hallmarks of Cancer structured in 2 main arms: tumor-autonomous vs non-autonomous traits
  • Easy to read language, containing appealing illustrations, respecting the scientific accuracy

Part of the book series: Learning Materials in Biosciences (LMB)

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Table of contents (10 chapters)

  1. Front Matter

    Pages I-IX
  2. Cancer as an Evolutionary Process

    • Lília Perfeito
    Pages 21-30
  3. Cell Signaling in Cancer

    • João T. Barata, Mariana L. Oliveira
    Pages 31-49
  4. The Cell Cycle, Cytoskeleton and Cancer

    • Irina S. Fonseca, Mónica Bettencourt-Dias
    Pages 51-74
  5. Genomic Instability: DNA Repair and Cancer

    • Ana Rita Carlos
    Pages 75-96
  6. Cell Metabolism in Cancer: An Energetic Switch

    • Inês Pimenta de Castro
    Pages 97-116
  7. Cancer Immunoediting and Hijacking of the Immune System

    • Vanda Póvoa, Rita Fior
    Pages 117-139
  8. Angiogenesis – Vessels Recruitment by Tumor Cells

    • Ana Magalhães, Sergio Dias
    Pages 141-157

About this book

This textbook takes you on a journey to the basic concepts of cancer biology. It combines developmental, evolutionary and cell biology perspectives, to then wrap-up with an integrated clinical approach.

The book starts with an introductory chapter, looking at cancer in a nut shell. The subsequent chapters are detailed and the idea of cancer as a mass of somatic cells undergoing a micro-evolutionary Darwinian process is explored. Further, the main Hanahan and Weinberg “Hallmarks of Cancer” are revisited.  In most chapters, the fundamental experiments that led to key concepts, connecting basic biology and biomedicine are highlighted. In the book’s closing section all of these concepts are integrated in clinical studies, where molecular diagnosis as well as the various classical and modern therapeutic strategies are addressed.

The book is written in an easy-to-read language, like a one-on-one conversation between the writer and the reader, without compromising the scientific accuracy. Therefore, this book is suited not only for advanced undergraduates and master students but also for patients or curious lay people looking for a further understanding of this shattering disease

Editors and Affiliations

  • Champalimaud Centre for the Unknown, Champalimaud Foundation, Lisbon, Portugal

    Rita Fior

  • Faculdade de Ciências da Universidade de Lisboa, Lisbon, Portugal

    Rita Zilhão

About the editors

Professor Dr. Rita Fior teaches Molecular and Cell Biology of Cancer at the Faculty of Sciences in the University of Lisbon, Portugal. She is also a Principal Investigator at the Champalimaud Foundation, a renowned state-of-the-art center for Science. She has worked with Julian Lewis (Emeritus Scientist and Fellow of the Royal Society, CRUK). 

Professor Dr. Rita Zilhão has been teaching for more than 20 years at the Faculty of Sciences in the University of Lisbon, Portugal. At this moment she is responsible for 3 courses: Genetic and Molecular Biology, Basics of Molecular Biology and Molecular and Cell Biology of Cancer. She is the coordinator of the Molecular and Genetic Biology Bachelor Program. 

Bibliographic Information

Buy it now

Buying options

eBook USD 79.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 99.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access