Population Genomics: Microorganisms

1. Front Matter

   Pages i-xiii

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2. Concepts and Approaches

   1. Front Matter

      Pages 1-1

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   2. Computational Methods in Microbial Population Genomics

      • Xavier Didelot

      Pages 3-29

   3. What Microbial Population Genomics Has Taught Us About Speciation

      • B. Jesse Shapiro

      Pages 31-47

   4. Peering into the Genetic Makeup of Natural Microbial Populations Using Metagenomics

      • Vincent J. Denef

      Pages 49-75

   5. A Reverse Ecology Framework for Bacteria and Archaea

      • Philip Arevalo, David VanInsberghe, Martin F. Polz

      Pages 77-96

3. Population Genomics of Bacteria and Archaea

   1. Front Matter

      Pages 97-97

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   2. What Is a Pseudomonas syringae Population?

      • David A. Baltrus

      Pages 99-121

   3. An Introductory Narrative to the Population Genomics of Pathogenic Bacteria, Exemplified by Neisseria meningitidis

      • Kanny Diallo, Martin C. J. Maiden

      Pages 123-143

   4. Population Genomics of Archaea: Signatures of Archaeal Biology from Natural Populations

      • David J. Krause, Rachel J. Whitaker

      Pages 145-155

4. Population Genomics of Fungi

   1. Front Matter

      Pages 157-157

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   2. Advances in Genomics of Human Fungal Pathogens

      • Daniel Raymond Kollath, Marcus de Melo Teixeira, Bridget Marie Barker

      Pages 159-206

   3. Yeast Population Genomics Goes Wild: The Case of Saccharomyces paradoxus

      • Mathieu Hénault, Chris Eberlein, Guillaume Charron, Éléonore Durand, Lou Nielly-Thibault, Hélène Martin et al.

      Pages 207-230

5. Population Genomics of Viruses

   1. Front Matter

      Pages 231-231

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   2. Population Genomics of Plant Viruses

      • Israel Pagán, Fernando García-Arenal

      Pages 233-265

   3. Population Genomics of Human Viruses

      • Fernando González-Candelas, Juan Ángel Patiño-Galindo, Carlos Valiente-Mullor

      Pages 267-296

   4. Population Genomics of Bacteriophages

      • Harald Brüssow

      Pages 297-334

6. Back Matter

   Pages 335-344

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Population genomics is a rapidly emerging field that has the potential to transform our understanding of how evolutionary forces shape genomic diversity among microbes.  There have already been considerable advances in understanding gene flow and spread of adaptive traits, and in linking epidemiology with evolutionary biology. The current challenge is to find unifying evolutionary principles for organisms that display a wide range of reproductive biology – from highly clonal to promiscuous – and for which the vast majority have eluded cultivation.  This requires interdisciplinary approaches that incorporate novel computational tools, testing of existing and novel population genetic models, and creative new ways of linking genetic diversity to ecological factors. This pioneering book will discuss the advances made and promises of population genomics in microorganisms, outlining some of the key theoretical and practical challenges for microbial population genomics, including defining and identifying populations, genomics-based reverse ecology and building appropriate tools to understand microbes in a variety of complex environments.

• Population structure
• Speciation
• Adaptation
• Epidemiology
• Evolution

• Department of Civil and Environmental Engineering, Massachusetts Institute of Technology, Cambridge, USA

  Martin F. Polz

• Faculty of Forestry and Environmental Management, University of New Brunswick, Fredericton, Canada

  Om P. Rajora

Dr. Martin Polz
Department of Civil and Environmental Engineering

Massachusetts Institute of Technology
Cambridge, MA
USA


Dr. Om P. Rajora
Professor
University of New Brunswick
Fredericton, NB E3C 5A3
Canada

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