Biological Microarrays

1. Front Matter

   Pages i-xi

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2. Application of Biological Microarray

   1. Front Matter

      Pages 1-1

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   2. RNA and DNA Microarrays

      • Stuart C. Sealfon, Tearina T. Chu

      Pages 3-34

   3. Aptamer Arrays

      • Eva Baldrich

      Pages 35-54

   4. Oligonucleotide Microarrays for Identification of Microbial Pathogens and Detection of Their Virulence-Associated or Drug-Resistance Determinants

      • Dmitriy V. Volokhov, Hyesuk Kong, Keith Herold, Vladimir E. Chizhikov, Avraham Rasooly

      Pages 55-94

   5. Protein Microarrays Printed from DNA Microarrays

      • Oda Stoevesandt, Mingyue He, Michael J. Taussig

      Pages 95-106

   6. Lithographically Defined Two- and Three-Dimensional Tissue Microarrays

      • Esther W. Gomez, Celeste M. Nelson

      Pages 107-116

   7. Ratiometric Lectin Microarray Analysis of the Mammalian Cell Surface Glycome

      • Ku-Lung Hsu, Kanoelani Pilobello, Lakshmipriya Krishnamoorthy, Lara K. Mahal

      Pages 117-131

   8. Cell Microarrays Based on Hydrogel Microstructures for the Application to Cell-Based Biosensor

      • Won-Gun Koh

      Pages 133-145

   9. Fabrication of Bacteria and Virus Microarrays Based on Polymeric Capillary Force Lithography

      • Pil J. Yoo

      Pages 147-160

   10. 3D Polymer Scaffold Arrays

       • Carl G. Simon Jr., Yanyin Yang, Shauna M. Dorsey, Murugan Ramalingam, Kaushik Chatterjee

       Pages 161-174

3. Methods for Microarray Generation

   1. Front Matter

      Pages 175-175

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   2. PDMS Microfluidic Capillary Systems for Patterning Proteins on Surfaces and Performing Miniaturized Immunoassays

      • Mateu Pla-Roca, David Juncker

      Pages 177-194

   3. Merging Photolithography and Robotic Protein Printing to Create Cellular Microarrays

      • Ji Youn Lee, Alexander Revzin

      Pages 195-206

   4. Generation of Protein and Cell Microarrays on Functionalized Surfaces

      • Yoo Seong Choi, Chang-Soo Lee

      Pages 207-217

   5. Microprinting of Liver Micro-organ for Drug Metabolism Study

      • Robert C. Chang, Kamal Emami, Antony Jeevarajan, Honglu Wu, Wei Sun

      Pages 219-238

   6. Microcontact Printing

      • Yunyan Xie, Xingyu Jiang

      Pages 239-248

   7. Micromolding for the Fabrication of Biological Microarrays

      • Ashley L. Galloway, Andrew Murphy, Jason P. Rolland, Kevin P. Herlihy, Robby A. Petros, Mary E. Napier et al.

      Pages 249-260

   8. Progress Report on Microstructured Surfaces Based on Chemical Vapor Deposition

      • Yaseen Elkasabi, Joerg Lahann

      Pages 261-279

   9. Methods for Forming Human Microvascular Tubes In Vitro and Measuring Their Macromolecular Permeability

      • Gavrielle M. Price, Joe Tien

      Pages 281-293

Recent developments in microarray technology have changed the landscape of biology and biomedical research, and they have revolutionized RNA and DNA research. In Biological Microarrays: Methods and Protocols, expert researchers explore exciting new developments in the field, providing a comprehensive approach to biological microarrays that conveys not only the state-of-the-art fundamentals, but also includes applications of the most innovative methods. Chapters address both the application of biological microarrays, including DNA/RNA, apatmer, proteins, tissues, oligonucleotides, carbohydrates, biomaterials, cells, bacteria, and virus microarrays, and also explore the different techniques used for generating microarray platforms. Composed in the highly successful Methods in Molecular Biology™ series format, each chapter contains a brief introduction, step-by-step methods, a list of necessary materials, and a Notes section which shares tips on troubleshooting and avoiding known pitfalls. Wide-ranging and revolutionary, Biological Microarrays: Methods and Protocols serves as a primary source for academics, practitioners, and professionals in related fields, including biologists, biotechnologists, biochemists, analytical chemists, and biomedical, physical, and microsystems engineers, to name a few, appealing to all of those interested in the present and future state of biological microarray research.

• 3D Polymer Scaffold Arrays
• Aptamer Arrays
• Bacteria Microarrays
• DNA Microarrays
• Microarray Bioinformatics
• Microcontact Printing
• Micromolding
• RNA Microarrays

• , MIT Division of Health Sciences and Tech, Harvard Medical School, Cambridge, USA

  Ali Khademhosseini

• , Department of Mechanical and Aerospace E, Seoul National University, Seoul, Korea, Republic of (South Korea)

  Kahp-Yang Suh

• Biophage Pharma, Inc., Montreal, Canada

  Mohammed Zourob

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