Dynamic Brain Imaging

1. Front Matter

   Pages i-xviii

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2. Introduction

   1. Front Matter

      Pages 1-1

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   2. Dynamic Imaging of Brain Function

      • Fahmeed Hyder

      Pages 3-21

   3. Fractal Characterization of Complexity in Dynamic Signals: Application to Cerebral Hemodynamics

      • Peter Herman, Laszlo Kocsis, Andras Eke

      Pages 23-40

3. Optical Imaging

   1. Front Matter

      Pages 41-41

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   2. Wide-Field and Two-Photon Imaging of Brain Activity with Voltage and Calcium-Sensitive Dyes

      • Ryota Homma, Bradley J. Baker, Lei Jin, Olga Garaschuk, Arthur Konnerth, Lawrence B. Cohen et al.

      Pages 43-79

   3. Two-Photon Imaging of Capillary Blood Flow in Olfactory Bulb Glomeruli

      • Pascale Tiret, Emmanuelle Chaigneau, Jérôme Lecoq, Serge Charpak

      Pages 81-91

   4. Astrocytic Calcium Signaling: Mechanism and Implications for Functional Brain Imaging

      • Xiaohai Wang, Takahiro Takano, Maiken Nedergaard

      Pages 93-109

   5. Using the Light Scattering Component of Optical Intrinsic Signals to Visualize In Vivo Functional Structures of Neural Tissues

      • Uma Maheswari Rajagopalan, Kazushige Tsunoda, Manabu Tanifuji

      Pages 111-132

4. Electrophysiology

   1. Front Matter

      Pages 133-133

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   2. Methods for Studying Functional Interactions Among Neuronal Populations

      • Nandakumar S. Narayanan, Mark Laubach

      Pages 135-165

   3. Magnetoencephalography (MEG)

      • Andreas A. Ioannides

      Pages 167-188

   4. Functional Neuroimaging of Spike-Wave Seizures

      • Joshua E. Motelow, Hal Blumenfeld

      Pages 189-209

5. Functional Magnetic Resonance Imaging (fMRI)

   1. Front Matter

      Pages 211-211

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   2. Tactile and Non-tactile Sensory Paradigms for fMRI and Neurophysiologic Studies in Rodents

      • Basavaraju G. Sanganahalli, Christopher J. Bailey, Peter Herman, Fahmeed Hyder

      Pages 213-242

   3. Using fMRI for Elucidating Dynamic Interactions

      • Yul-Wan Sung, Seiji Ogawa

      Pages 243-254

   4. Resting-State Functional Connectivity in Animal Models: Modulations by Exsanguination

      • Bharat B. Biswal, Sridhar S. Kannurpatti

      Pages 255-274

6. Alternate Magnetic Resonance Methods

   1. Front Matter

      Pages 275-275

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   2. Dynamic Magnetic Resonance Imaging of Cerebral Blood Flow Using Arterial Spin Labeling

      • Afonso C. Silva, Fernando F. Paiva

      Pages 277-295

   3. Dynamic MRI of Small Electrical Activity

      • Allen W. Song, Trong-Kha Truong, Marty Woldorff

      Pages 297-315

If a picture is worth a thousand words, then dynamic images of brain activity certainly warrant many, many more. This book will help users learn to decipher the dynamic imaging data that will be critical to our future understanding of complex brain functions. In recent years, there have been unprecedented methodological advancements in the imaging of brain activity. These techniques allow the measurement of everything from neural activity (e.g., membrane potential, ion ?ux, neurotransmitter ?ux) to energy metabolism (e.g., glucose consumption, oxygen consumption, creatine kinase ?ux) and functional hyperemia (e.g., blood ?ow, volume, oxygenation). This book deals with a variety of magnetic resonance, electrophysiology, and optical methods that are often used to measure some of these dynamic processes. All chapters were written by leading experts, spanning three continents, specializing in state-of-the-art methods. Brie?y, the book has ?ve sections. In the introductory section, there are two chapters; the ?rst one contains a brief pre- ble to dynamic brain imaging and the other presents a novel, analytical approach to processing of dynamically acquired data. The second section has four chapters and delves into a wide range of optical imaging methods. I am privileged to include a chapter from Lawrence B. Cohen, considered by many to be the authority on optical imaging and spectroscopy, both in vitro and in vivo [Cohen LB (1973) Physiol Rev.

• Brain activity
• Cortex
• Electrophysiology
• Magnetic resonance
• Optical imaging
• brain imaging
• fMRI
• magnetic resonance spectroscopy
• physiology
• Diagnostic Radiology

From the reviews:

"The title follows a similar review of Dynamic Brain Imaging, with an emphasis on methods and protocols. The stated goal of this book is to ‘… help users learn to decipher the dynamic imaging data.’ … Overall … chapters were well written and accomplished their intended goal of educating the reader about the various dynamic imaging methodologies at various stages of development. … In summary, this review of multimodal in vivo brain imaging methods provides a nice compilation of manuscripts … ." (American Journal of Neuroradiology, Vol. 30, May, 2009)

• Yale University, New Haven, USA

  Fahmeed Hyder

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