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Biomedical Informatics

  • Book
  • © 2009

Overview

Editors:
  1. Vadim Astakhov

    1. Biomedical Informatics Research Network, University of California, San Diego, La Jolla, U.S.A.

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  • Features cutting-edge methods for information and knowledge discovery in bio-medical research
  • Includes modern methods of software design and software engineering in the area of bio- and neuro- informatics
  • Provides descriptions of modern architectures for the development of scientific cyber infrastructures

Part of the book series: Methods in Molecular Biology (MIMB, volume 569)

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Table of contents (12 protocols)

  1. Front Matter

    Pages ii-ix
    Download chapter PDF

  2. Management of Information in Distributed Biomedical Collaboratories

    • David B. Keator
    Pages 1-23

  3. Enabling Public Data Sharing: Encouraging Scientific Discovery and Education

    • Christine Fennema-Notestine
    Pages 25-32

  4. Mediator Infrastructure for Information Integration and Semantic Data Integration Environment for Biomedical Research

    • Jeffrey S. Grethe, Edward Ross, David Little, Brian Sanders, Amarnath Gupta, Vadim Astakhov
    Pages 33-53

  5. System Biology of Gene Regulation

    • Michael Baitaluk
    Pages 55-87

  6. Current Computational Methods for Prioritizing Candidate Regulatory Polymorphisms

    • Stephen Montgomery
    Pages 89-114

  7. Methods of Information Geometry in Computational System Biology (Consistency between Chemical and Biological Evolution)

    • Vadim Astakhov
    Pages 115-127

  8. Protein Structure Prediction Based on Sequence Similarity

    • Lukasz Jaroszewski
    Pages 129-156

  9. Applications of Bioinformatics to Protein Structures: How Protein Structure and Bioinformatics Overlap

    • Gye Won Han, Chris Rife, Michael R. Sawaya
    Pages 157-172

  10. Knowledge Discovery via Machine Learning for Neurodegenerative Disease Researchers

    • I. Burak Özyurt, Gregory G. Brown
    Pages 173-196

  11. Brain Model of Text Animation as a Data Mining Strategy

    • Tamara Astakhova, Vadim Astakhov
    Pages 197-217

  12. Processes Parallel Execution Using Grid Wizard Enterprise

    • Marco Ruiz
    Pages 219-238

  13. Single Sign-On in a Grid Portal

    • Ramil V. Manansala
    Pages 239-262

  14. Back Matter

    Pages 263-270
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Keywords

About this book

In past decades, the area of bioinformatics has proved to be both dynamic and vital, producing a wide spectrum of novel approaches and assuming an increasingly important role in modern bio-technological development. In Biomedical Informatics, expert researchers explore cutting-edge new advances in the field, providing an overview of novel cyberinfrastructures which are currently under development in various bio-medical centers across the world. Chapters demonstrate  various architectures for large-scale collaboration, offer modern approaches currently used in various areas of bioinformatics, and highlight the software challenges associated with large-scale biomedical informatics. Composed in the highly successful Methods in Molecular Biology™ series format, chapters include a brief introduction, detailed methods, and a Notes section which shares tips on troubleshooting and avoiding known pitfalls.

Wide-ranging and innovative, Biomedical Informatics is an essential manual for newcomers to this area, as well as an invaluable addition to the laboratories and offices of the most practiced researchers.

Reviews

From the reviews: “Technicians and researchers from San Diego, California survey novel cyber-infrastructures that are currently under development in various biomedical centers around the world. They describe several architectures for large-scale collaboration across multiple centers, modern approaches in various areas of bioinformatics, and software challenges and strategies for overcoming them. … The material could be helpful to practitioners working in bioinformatics or students preparing for it.” (SciTech Book News, March, 2010) “This volume in the Methods in Molecular Biology series provides an overview of novel cyberinfrastructures that are fundamental to present-day biomedical informatics. … Scientists involved in biomedical informatics … who are active in the field of biomedical research are the intended audience. This includes both first-time and seasoned students and biomedical researchers who are interested in using informatics technologies in their laboratories. … This is an excellent contribution to the literature dedicated to the study of bioinformatics in biomedical sciences.” (Ruben Mestril, Doody’s Review Service, February, 2010)

Editors and Affiliations

  • Biomedical Informatics Research Network, University of California, San Diego, La Jolla, U.S.A.

    Vadim Astakhov

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