Managing Failed Anti-Reflux Therapy

1. Front Matter

   Pages i-x

   PDF

2. The Epidemiology and Pathophysiology of Gastroesophageal Reflux Disease

   • Peter J. Kahrilas, John E. Pandolfino

   Pages 1-13

3. History of Medical and Surgical Anti-Reflux Therapy

   • Mark K. Ferguson

   Pages 15-29

4. Medical Management of GERD: Algorithms and Outcomes

   • David A. Johnson

   Pages 31-43

5. Complications of GERD: Esophagitis, Stricture, Barrett’s, and Cancer

   • John A. Bonino, Prateek Sharma

   Pages 45-55

6. Principles of Successful Surgical Anti-Reflux Procedures

   • Federico Cuenca-Abente, Brant K. Oelschlager, Carlos A. Pellegrini

   Pages 57-65

7. Acute Complications of Anti-Reflux Surgery

   • Gianmattia del Genio, Jean-Marie Collard

   Pages 67-77

8. Persistent Symptoms after Anti-Reflux Surgery and their Management

   • John G. Hunter, M. Brian Fennerty

   Pages 79-89

9. Technical Surgical Failures: Presentation, Etiology and Evaluation

   • Carrie A. Sims, David W. Rattner

   Pages 91-102

10. Symptoms after Anti-Reflux Surgery: Everything Is Not always caused by Surgery

    • Kenneth R. DeVault

    Pages 103-111

11. The Medical and Endoscopic Management of Failed Surgical Anti-Reflux Procedures

    • M. Brian Fennerty, John G. Hunter

    Pages 113-125

12. Reoperation for Failed Anti-Reflux Surgery

    • Jennefer A. Kieran, Myriam J. Curet

    Pages 127-138

13. Management of Alkaline Reflux

    • Jose M. Clavero, Philippe Topart, Claude Deschamps

    Pages 139-149

14. Management of the Short Esophagus

    • Éric Fréchette, André Duranceau

    Pages 151-162

15. Esophagectomy: Indications, Techniques, and Outcomes

    • Mark K. Ferguson

    Pages 163-173

16. Vagal Sparing Esophagectomy

    • Steven R. DeMeester

    Pages 175-180

17. Future Directions of Therapy for GERD

    • M. Brian Fennerty, Mark K. Ferguson

    Pages 181-185

18. Back Matter

    Pages 187-196

    PDF

th Although GERD was initially described in the early 19 century,it is essentially a c- sequence of our modern day largesse. Dietary factors and associated obesity have c- bined with as yet other unknown factors (e. g. a decrease in the prevalence of H. pylori?) to make GERD one of the most common diseases affecting western society. It is es- mated that up to 20 million adults in the United States suffer from GERD,and treatment of these individuals consumes approximately $10 billion annually,the majority of it for prescription drugs used to manage the disease and its symptoms. Fortunately, despite challenges presented by co-factors resulting in GERD (diet, obesity, etc. ), therapy of GERD is largely successful. However, even a low failure rate for a therapy used in the management of GERD still results in large numbers of affected patients because of the high prevalence of this disease. Use of a conservative estimate of a failure rate of 5% translates to 1 million ineffectively treated and unhappy patients. How to manage these patients is the subject of this book. Why is publication of this book important now? Several factors prompted us to work on this project. Mature results for proton pump inhibitor use are available,making this an appropriate time to review outcomes of PPI therapy of GERD. Similarly,mature results are now available for minimally invasive surgical therapy for GERD.

• Antireflux Therapy
• Gastroesophageal Reflux Disease (GERD)
• Surgery
• cancer
• endoscopy
• gastroenterology
• thoracic surgery

From the reviews of the first edition:

"An outstanding review of an increasingly common clinical problem, namely, the management of field antireflux therapy. The selection of chapter authors is outstanding, the combinations of topics presented are well thought out and the layout and presentation are excellent. Clinicians who see patients on any form of GERD therapy will find the book insightful, scholarly and useful."

J.H. Peters, MD, FACS, Diseases of the Esophagus

"This is a multi-authored textbook edited by a surgeon and a gastroenterologist. … The content and references are up-to-date. The quality of the drawings, black and white and colour illustrations is generally excellent throughout the book. … This is a useful and comprehensive textbook for surgeons who want to manage such complex patients and understand the importance of a truly multidisciplinary approach." (L. Bonavina, Digestive and Liver Disease, Issue 38, 2006)

• Professor of Surgery, Head, Thoracic Surgery Service, Department of Surgery, University of Chicago, Chicago, IL, USA

  Mark K. Ferguson

• Professor of Medicine, Division of Gastroenterology, Department of Medicine, Oregon Health & Science University, Portland, OR, USA

  M. Brian Fennerty

Policies and ethics