Editors:
- Fully updated from the popular first edition
- Features easy-to-follow protocols that are ready for the laboratory
- Contains expert tips and key implementation advice to ensure successful results
Part of the book series: Methods in Molecular Biology (MIMB, volume 1015)
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Table of contents (23 protocols)
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Front Matter
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Introduction to Pharmacogenomics
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Front Matter
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Techniques for Interrogating Variation in Human Genes and Genomes
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Front Matter
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Functional Assessment of Genetic Variation: In Vitro and In Vivo Methods
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Front Matter
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About this book
Understanding an individual's genetic makeup is the key to creating personalized drugs with greater efficacy and safety, and pharmacogenomics aims to study the complex genetic basis of inter-patient variability in response to drug therapy. Based upon the success of its first edition, the second edition of Pharmacogenomics: Methods And Protocols aims to continue providing readers with high-quality content on the most innovative and commonly adopted technologies in the field of pharmacogenomics as presented by experts in the field. Broken into several sections, this detailed volume examines techniques for interrogating variation in human genes and genomes, functional assessment of genetic variation, both in vitro and in vivo, as well as tools for translation and implementation of pharmacogenetic markers. Written in the highly successful Methods in Molecular Biology™ series format, chapters include introductions to the respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls.
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Comprehensive and thoroughly updated, Pharmacogenomics: Methods And Protocols, Second Edition serves as an essential reference and an invaluable source on the latest information in this field.Editors and Affiliations
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Institute for Pharmacogenomics, and Individualized Therapy, University of North Carolina, Chapel Hill, USA
Federico Innocenti
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, Dept. of Clinical Chemistry (AKC), Erasmus MC, Rotterdam, Netherlands
Ron H.N. Schaik
Bibliographic Information
Book Title: Pharmacogenomics
Book Subtitle: Methods and Protocols
Editors: Federico Innocenti, Ron H.N. Schaik
Series Title: Methods in Molecular Biology
DOI: https://doi.org/10.1007/978-1-62703-435-7
Publisher: Humana Totowa, NJ
eBook Packages: Springer Protocols
Copyright Information: Springer Science+Business Media, LLC 2013
Hardcover ISBN: 978-1-62703-434-0Published: 04 July 2013
Softcover ISBN: 978-1-4939-5935-8Published: 23 August 2016
eBook ISBN: 978-1-62703-435-7Published: 04 July 2013
Series ISSN: 1064-3745
Series E-ISSN: 1940-6029
Edition Number: 2
Number of Pages: XIII, 359
Number of Illustrations: 23 b/w illustrations, 33 illustrations in colour
Topics: Pharmacology/Toxicology, Human Genetics