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Protein Kinase Technologies

  • Book
  • © 2012

Overview

Editors:
  1. Hideyuki Mukai

    1. Biosignal Research Center, Kobe University, Kobe, Japan

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  • Serves as a navigational guide in the exploration of protein kinase signaling in neuroscience
  • Provides practical instructions and thought-provoking reviews
  • Fosters cross-talk among investigators studying different protein kinases
  • Includes supplementary material: sn.pub/extras

Part of the book series: Neuromethods (NM, volume 68)

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Table of contents (19 protocols)

  1. Front Matter

    Pages i-xiii
    Download chapter PDF

  2. Recent General Methodologies

    1. Front Matter

      Pages 1-1
      Download chapter PDF

    2. Visualization of Protein Kinase Activities in Living Cells

      • Kazuhiro Aoki, Naoki Komatsu, Akihiro Goto, Michiyuki Matsuda
      Pages 3-12

    3. Phos-tag Affinity Electrophoresis for Protein Kinase Profiling

      • Eiji Kinoshita, Emiko Kinoshita-Kikuta, Tohru Koike
      Pages 13-34

    4. Large-Scale Protein Phosphorylation Analysis by Mass Spectrometry-Based Phosphoproteomics

      • Wei-Chi Ku, Naoyuki Sugiyama, Yasushi Ishihama
      Pages 35-46

  3. Individual Protein Kinases

    1. Front Matter

      Pages 47-47
      Download chapter PDF

    2. Ca2+/Calmodulin-Dependent Protein Kinase II (CaMKII)

      • Steven J. Coultrap, K. Ulrich Bayer
      Pages 49-72

    3. CASK: A Specialized Neuronal Kinase

      • Konark Mukherjee
      Pages 73-85

    4. Cyclin-Dependent Kinase 5 (Cdk5): Preparation and Measurement of Kinase Activity

      • Seiji Minegishi, Taro Saito, Shin-ichi Hisanaga
      Pages 87-103

    5. ErbB Membrane Tyrosine Kinase Receptors: Analyzing Migration in a Highly Complex Signaling System

      • Nicole M. Brossier, Stephanie J. Byer, Lafe T. Peavler, Steven L. Carroll
      Pages 105-131

    6. The Extracellular Signal-Regulated Kinase (ERK) Cascade in Neuronal Cell Signaling

      • Daniel Orellana, Ilaria Morella, Marzia Indrigo, Alessandro Papale, Riccardo Brambilla
      Pages 133-152

    7. Glycogen Synthase Kinase-3 in Neurological Diseases

      • Oksana Kaidanovich-Beilin, James Robert Woodgett
      Pages 153-188

    8. Cortical Neurons Culture to Study c-Jun N-Terminal Kinase Signaling Pathway

      • Alessandra Sclip, Xanthi Antoniou, Tiziana Borsello
      Pages 189-202

    9. MuSK: A Kinase Critical for the Formation and Maintenance of the Neuromuscular Junction

      • Arnab Barik, Wen-cheng Xiong, Lin Mei
      Pages 203-217

    10. Assays for Pten-Induced Novel Kinase 1 (PINK1) and Leucine-Rich Repeat Kinase 2 (LRRK2), Kinases Associated with Parkinson’s Disease

      • Alexandra Beilina, Mark R. Cookson
      Pages 219-236

    11. Imaging PKA Activation Inside Neurons in Brain Slice Preparations

      • Marina Brito, Elvire Guiot, Pierre Vincent
      Pages 237-250

    12. Imaging Oscillations of Protein Kinase C Activity in Cells

      • Maya T. Kunkel, Alexandra C. Newton
      Pages 251-257

    13. Diacylglycerol Kinase (DGK) as a Regulator of PKC

      • Yasuhito Shirai, Naoaki Saito
      Pages 259-271

    14. Trafficking of Trk Receptors

      • Daniel Bodmer, Rejji Kuruvilla
      Pages 273-289

    15. Mammalian Target of Rapamycin

      • Lukasz J. Swiech, Malgorzata Urbanska, Matylda Macias, Agnieszka Skalecka, Jacek Jaworski
      Pages 291-318
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Keywords

About this book

Divided into two convenient sections, Protein Kinase Technologies collects contributions from experts in the field examining recent methodologies and techniques generally applicable to protein kinase research as well as to individual protein kinases which require special attention in neuroscience.  These chapters will not only be practical instructions useful for readers' daily work in setting up and performing research but also thought-provoking and enjoyable reviews of recent advancements of individual protein kinases in neuroscience.  Written for the highly successful Neuromethods series, this work contains the kind of detailed description and implementation advice that is crucial for getting optimal results.

 

Authoritative and accessible, Protein Kinase Technologies seeks to foster cross-talk among investigators who study different protein kinases, and will also be beneficial for the entry of new investigators into this pivotal field.

Editors and Affiliations

  • Biosignal Research Center, Kobe University, Kobe, Japan

    Hideyuki Mukai

Bibliographic Information

  • Book Title: Protein Kinase Technologies

  • Editors: Hideyuki Mukai

  • Series Title: Neuromethods

  • DOI: https://doi.org/10.1007/978-1-61779-824-5

  • Publisher: Humana Totowa, NJ

  • eBook Packages: Springer Protocols

  • Copyright Information: Springer Science+Business Media, LLC 2012

  • Hardcover ISBN: 978-1-61779-823-8Published: 31 May 2012

  • Softcover ISBN: 978-1-4939-6242-6Published: 04 May 2017

  • eBook ISBN: 978-1-61779-824-5Published: 14 June 2012

  • Series ISSN: 0893-2336

  • Series E-ISSN: 1940-6045

  • Edition Number: 1

  • Number of Pages: XIV, 366

  • Number of Illustrations: 35 b/w illustrations, 35 illustrations in colour

  • Topics: Neurosciences, Human Physiology

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