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  • Book
  • © 2012

Chemical Genomics and Proteomics

Reviews and Protocols

  • Focuses on the foremost, current technologies being used in the fields of chemical genomics and proteomics
  • Includes clear and concise laboratory protocols, ready for use
  • Features expert tips and implementation advice to ensure successful results
  • Includes supplementary material: sn.pub/extras

Part of the book series: Methods in Molecular Biology (MIMB, volume 800)

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Table of contents (15 protocols)

  1. Front Matter

    Pages i-xi
  2. Reviews

    1. Front Matter

      Pages 1-1
    2. Overview of Chemical Genomics and Proteomics

      • Edward D. Zanders
      Pages 3-10
    3. In Silico Design of Small Molecules

      • Paul H. Bernardo, Joo Chuan Tong
      Pages 25-31
    4. Surface Plasmon Resonance for Proteomics

      • Nico J. de Mol
      Pages 33-53
  3. Protocols

    1. Front Matter

      Pages 55-55
    2. Biomimetic Affinity Ligands for Immunoglobulins Based on the Multicomponent Ugi Reaction

      • Graziella El Khoury, Laura A. Rowe, Christopher R. Lowe
      Pages 57-74
    3. Electrochemical Aptamer Sensor for Small Molecule Assays

      • Xin Liu, Wang Li, Xiahong Xu, Jiang Zhou, Zhou Nie
      Pages 119-132
    4. Miniaturized, Microarray-Based Assays for Chemical Proteomic Studies of Protein Function

      • Jonathan M. Blackburn, Aubrey Shoko, Natasha Beeton-Kempen
      Pages 133-162
    5. Glycan Microarrays

      • Xuezheng Song, Jamie Heimburg-Molinaro, David F. Smith, Richard D. Cummings
      Pages 163-171
    6. Systems for the Cell-Free Synthesis of Proteins

      • Lei Kai, Christian Roos, Stefan Haberstock, Davide Proverbio, Yi Ma, Friederike Junge et al.
      Pages 201-225
    7. Protein Identification by MALDI-TOF Mass Spectrometry

      • Judith Webster, David Oxley
      Pages 227-240
  4. Back Matter

    Pages 241-243

About this book

Chemical genomics technology has been steadily improving, delivering new biological probes and drugs, and the explicit use of the term ‘chemical proteomics’ has increased with it, as proteins have always been at the heart of this technology.  In Chemical Genomics and Proteomics: Reviews and Protocols, experts in the field present updated reviews of the chemistry of small molecules and their interaction with protein targets as well as detailed protocols that cover different types of ligands, carbohydrates, and lipids.  For example, the generation of their protein targets and methods for measuring their interactions is covered.  Written in the highly successful Methods in Molecular Biology™ series format, methodology chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

 

Thorough and up to date,  Chemical Genomics and Proteomics: Reviews and Protocols aims to provide inspiration to those who wish to use chemical genomics and proteomics in their work and develop this young field into full maturity through the incorporation of the new biological and chemical technologies beginning to emerge here.

Editors and Affiliations

  • Royston, United Kingdom

    Edward D. Zanders

Bibliographic Information

  • Book Title: Chemical Genomics and Proteomics

  • Book Subtitle: Reviews and Protocols

  • Editors: Edward D. Zanders

  • Series Title: Methods in Molecular Biology

  • DOI: https://doi.org/10.1007/978-1-61779-349-3

  • Publisher: Humana Totowa, NJ

  • eBook Packages: Springer Protocols

  • Copyright Information: Springer Science+Business Media, LLC 2012

  • Hardcover ISBN: 978-1-61779-348-6Published: 01 October 2011

  • Softcover ISBN: 978-1-4939-6226-6Published: 23 August 2016

  • eBook ISBN: 978-1-61779-349-3Published: 02 October 2011

  • Series ISSN: 1064-3745

  • Series E-ISSN: 1940-6029

  • Edition Number: 1

  • Number of Pages: XI, 243

  • Number of Illustrations: 71 b/w illustrations

  • Topics: Biochemistry, general, Proteomics, Gene Function

Buy it now

Buying options

eBook USD 84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 139.00
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 109.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access