Overview
- Includes cutting-edge methods and protocols
- Provides step-by-step detail essential for reproducible results
- Contains key notes and implementation advice from the experts
- Includes supplementary material: sn.pub/extras
Part of the book series: Methods in Molecular Biology (MIMB, volume 793)
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Table of contents (34 protocols)
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Front Matter
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Neural Cell Culture Techniques
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Front Matter
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Models of Neurodegeneration
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Front Matter
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Neurodegenerative Disease Mechanisms: Proteinopathies
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Front Matter
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Keywords
About this book
Neurodegenerative disorders, such as Alzheimer's and Parkinson's disease are a growing burden on our society. Understanding and treating these common diseases is one of the major current challenges for the biomedical field. In Neurodegeneration: Methods and Protocols, experts in the field tackle this challenge and present cutting-edge analytical and technological approaches to study the mechanisms underlying neurodegenerative processes. Organizes into five sections, chapters detail protocols for isolating and culturing cells from the nervous system, production and use of animal models, characterization of cell death, analytical tools to study disease mechanisms, and therapeutic approaches for neurodegeneration. Written in the successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls.
Authoritative and easily accessible, Neurodegeneration: Methods and Protocols serves as an ideal guide to both novice and professional researchers in the field of neurodegeneration.
Reviews
From the reviews:
“The authors describe various cell and molecular systems related to neurodegeneration research. … there are a lot of protocols and methods described by the book that can be used by medical students, graduate students, junior, and senior investigators. I heartily recommend this book to university and research institute communities working on neurodegeneration and regeneration.” (Joseph J. Grenier, Amazon.com, September, 2013)
“This is an authoritative collection of manuscripts tailored to bench scientists involved in neurodegenerative research. … It is intended for cell biologists, molecular biologists, biochemists, pathologists, and researchers in the field of neurodegeneration. … This book is most appropriate for the audience of basic scientists interested in the mechanics of experimental neurodegenerative work. For this audience, the book will find a suitable space on their lab benches.” (Joseph I. Sirven, Doody’s Book Reviews, April, 2012)Editors and Affiliations
Bibliographic Information
Book Title: Neurodegeneration
Book Subtitle: Methods and Protocols
Editors: Giovanni Manfredi, Hibiki Kawamata
Series Title: Methods in Molecular Biology
DOI: https://doi.org/10.1007/978-1-61779-328-8
Publisher: Humana Totowa, NJ
eBook Packages: Springer Protocols
Copyright Information: Springer Science+Business Media, LLC 2011
Hardcover ISBN: 978-1-61779-327-1Published: 15 September 2011
Softcover ISBN: 978-1-4939-6220-4Published: 23 August 2016
eBook ISBN: 978-1-61779-328-8Published: 15 September 2011
Series ISSN: 1064-3745
Series E-ISSN: 1940-6029
Edition Number: 1
Number of Pages: XV, 512
Topics: Neurosciences