Skip to main content
  • Book
  • © 2011

Animal Models of Movement Disorders

Volume II

  • Serves as a comprehensive and valuable reference for those studying motor disorders
  • Provides appropriate models and assessment tools
  • Includes clear, easy to follow methods with expert implementation advice

Part of the book series: Neuromethods (NM, volume 62)

Buy it now

Buying options

eBook USD 89.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 119.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access

This is a preview of subscription content, log in via an institution to check for access.

Table of contents (22 protocols)

  1. Front Matter

    Pages i-xv
  2. Basal Ganglia

    1. Front Matter

      Pages 1-1
    2. Behavioral Assessment of Genetic Mouse Models of Huntington’s Disease

      • Miriam A. Hickey, Marie-Françoise Chesselet
      Pages 3-19
    3. Excitotoxic Lesions of the Rodent Striatum

      • Máté D. Döbrössy, Fabian Büchele, Guido Nikkhah
      Pages 21-35
    4. Combination Lesion Models of MSA

      • Daniela Kuzdas, Gregor K. Wenning
      Pages 37-54
    5. The Role of the Dorsal Striatum in Instrumental Conditioning

      • Mark A. Rossi, Henry H. Yin
      Pages 55-69
    6. 3-Nitropropionic Acid and Other Metabolic Toxin Lesions of the Striatum

      • Cesar V. Borlongan, Paul R. Sanberg
      Pages 71-89
    7. Functional Assessment of Subcortical Ischemia

      • Tracy D. Farr, Rebecca C. Trueman
      Pages 91-114
  3. Neo- and Allo-Cortical Systems

    1. Front Matter

      Pages 115-115
    2. Functional Organization of Rat and Mouse Motor Cortex

      • G. Campbell Teskey, Bryan Kolb
      Pages 117-137
    3. Forebrain Circuits Controlling Whisker Movements

      • Kevin D. Alloway, Jared B. Smith
      Pages 139-159
    4. Photothrombotic Infarction of Caudate Nucleus and Parietal Cortex

      • Toshihiko Kuroiwa, Richard F. Keep
      Pages 183-191
    5. Models of Rodent Cortical Traumatic Brain Injury

      • Frances Corrigan, Jenna M. Ziebell, Robert Vink
      Pages 193-209
  4. Cerebellar and Brain Stem Systems

    1. Front Matter

      Pages 239-239
    2. Genetic Models of Cerebellar Dysfunction

      • Robert Lalonde, Catherine Strazielle
      Pages 241-262
    3. Cerebellar Control of Fine Motor Function

      • Rachel M. Sherrard
      Pages 263-279
    4. Cerebellum and Classical Conditioning

      • Richard F. Thompson
      Pages 281-286
    5. Assessments of Visual Function

      • Ma’ayan Semo, Carlos Gias, Anthony Vugler, Peter John Coffey
      Pages 287-320

About this book

Movement is the way that animals interact with their environment and is under the organization and complex control of the brain and spinal cord. Multiple central nervous systems, including cortex, basal ganglia, cerebellum, and brainstem, interact to provide precise motor control and integration. Damage or disease within these systems cause profound motor disturbances in man, which can be effectively modeled in animals to develop a better understanding and treatment of the human condition. Animal Models of Movement Disorders introduces a variety of methods and techniques used to model and assess motor function in experimental animals from lower orders, such as drosophila and c. elegans, through vertebrate species including fish, to mammals, such as rodents and non-human primates. The most advanced contemporary models in each system are presented at multiple levels of analysis from molecular and genetic modeling, lesions, anatomy, neurochemistry, to imaging and behavior. Volume II of this detailed collection contains sections on the basal ganglia, neo- and allo-cortical systems, cerebellar and brain stem systems, as well as spinal cord systems.

 

Comprehensive and meticulous, Animal Models of Movement Disorders serves as a valuable reference for those studying motor disorders by covering methodologies in detail and providing the information necessary to consider both the appropriate models and assessment tools that can most informatively answer the key experimental issues in the field.

Editors and Affiliations

  • , Welsh School of Pharmacology, Cardiff University, Cardiff, United Kingdom

    Emma L. Lane

  • School of Biosciences, Brain Repair Group, Cardiff University, Cardiff, United Kingdom

    Stephen B. Dunnett

Bibliographic Information

  • Book Title: Animal Models of Movement Disorders

  • Book Subtitle: Volume II

  • Editors: Emma L. Lane, Stephen B. Dunnett

  • Series Title: Neuromethods

  • DOI: https://doi.org/10.1007/978-1-61779-301-1

  • Publisher: Humana Totowa, NJ

  • eBook Packages: Springer Protocols

  • Copyright Information: Springer Science+Business Media, LLC 2011

  • Hardcover ISBN: 978-1-61779-300-4Published: 08 September 2011

  • Softcover ISBN: 978-1-4939-6294-5Published: 23 August 2016

  • eBook ISBN: 978-1-61779-301-1Published: 15 September 2011

  • Series ISSN: 0893-2336

  • Series E-ISSN: 1940-6045

  • Edition Number: 1

  • Number of Pages: XV, 443

  • Number of Illustrations: 48 b/w illustrations, 28 illustrations in colour

  • Topics: Neurosciences, Neurology, Animal Models

Buy it now

Buying options

eBook USD 89.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 119.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access