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Apoptosis, Cell Signaling, and Human Diseases

Molecular Mechanisms, Volume 1

  • Book
  • © 2007

Overview

Editors:
  1. Rakesh Srivastava

    1. Department of Biochemistry, University of Texas Health Center at Tyler, Tyler

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Table of contents (15 chapters)

  1. Front Matter

    Pages i-xvi
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  2. Malignant Transformation and Metastasis

    1. Front Matter

      Pages 1-1
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    2. BCR-ABL and Human Cancer

      • Maria Pérez-Caro, Isidro Sánchez-Garcia
      Pages 3-34

    3. Angiogenesis and Cancer

      • Yohei Maeshima
      Pages 35-61

    4. Metastasis

      • Christine E. Horak, Julie L. Bronder, Amina Bouadis, Patricia S. Steeg
      Pages 63-96

    5. Carcinogenesis

      • Dean G. Tang, James P. Kehrer
      Pages 97-118

    6. Aberrations of DNA Damage in Checkpoints in Cancer

      • Marikki Laiho
      Pages 119-136

    7. c-Myc, Apoptosis, and Disordered Tissue Growth

      • Michael Khan, Stella Pelengaris
      Pages 137-178

    8. Role of Lysophospholipids in Cell Growth and Survival

      • Xianjun Fang, Sarah Spiegel
      Pages 179-201

    9. Alternative Use of Signaling by the βGBP Cytokine in Cell Growth and Cancer Control

      • Livio Mallucci, Valerie Wells
      Pages 203-216

    10. Control Nodes Linking the Regulatory Networks of the Cell Cycle and Apoptosis

      • Baltazar D. Aguda, Wee Kheng Yio, Felicia Ng
      Pages 217-235

  3. Molecular Basis of Disease Therapy

    1. Front Matter

      Pages 237-237
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    2. Regulation of NF-κB Function

      • Daniel Sliva, Rakesh Srivastava
      Pages 239-262

    3. 5-Fluorouracil

      • Daniel B. Longley, Patrick G. Johnston
      Pages 263-278

    4. Apoptosis-Inducing Cellular Vehicles for Cancer Gene Therapy

      • Gergely Jarmy, Jiwu Wei, Klaus-Michael Debatin, Christian Beltinger
      Pages 279-302

    5. Apoptosis and Cancer Therapy

      • Maurice Reimann, Clemens A. Schmitt
      Pages 303-320

    6. Coupling Apoptosis and Cell Division Control in Cancer

      • Dario C. Altieri
      Pages 321-334

    7. Clinical Significance of Histone Deacetylase Inhibitors in Cancer

      • Sharmila Shankar, Rakesh K. Srivastava
      Pages 335-361

  4. Back Matter

    Pages 363-369
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Keywords

About this book

Apoptosis, Cell Signaling, and Human Diseases: Molecular Mechanisms, Volumes 1 and 2, present a concise synthesis of recent developments in the understanding of both cell survival and apoptotic pathways. Particular attention is given to apoptosis in human diseases, such as different forms of cancer and neurodegenerative diseases. These comprehensive volumes integrate the most innovative and current findings from several related disciplines of scientific research, including pathology, genetics, virology, cell biology, immunology, and molecular biology.

Volume 1 is divided into two sections: “Malignant Transformation and Metastasis” and “Molecular Basis of Disease Therapy.” Volume 2 follows a similar structure and is divided into sections entitled “Kinases and Phosphate” and “Molecular Basis of Cell Death.” All of the contributors are at the forefront of scientific discovery, and the reviews they present systemically examine the most exciting and innovative aspects of their particular areas of expertise. Researchers will find these volumes of major benefit as they search for novel and more effective treatments for human diseases.

Editors and Affiliations

  • Department of Biochemistry, University of Texas Health Center at Tyler, Tyler

    Rakesh Srivastava

Bibliographic Information

  • Book Title: Apoptosis, Cell Signaling, and Human Diseases

  • Book Subtitle: Molecular Mechanisms, Volume 1

  • Editors: Rakesh Srivastava

  • DOI: https://doi.org/10.1007/978-1-59745-200-7

  • Publisher: Humana Totowa, NJ

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Humana Press 2007

  • Hardcover ISBN: 978-1-58829-677-1Published: 02 February 2007

  • Softcover ISBN: 978-1-61737-713-6Published: 05 November 2010

  • eBook ISBN: 978-1-59745-200-7Published: 05 November 2007

  • Edition Number: 1

  • Number of Pages: 384

  • Number of Illustrations: 53 b/w illustrations, 4 illustrations in colour

  • Topics: Cell Biology, Biochemistry, general

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