Skip to main content
SpringerLink
Log in
Book cover

Microarrays in Clinical Diagnostics

  • Book
  • © 2005

Overview

Editors:
  1. Thomas O. Joos

    1. Biochemistry Department, NMI Natural and Medical Sciences Institute at the University of Tuebingen, Reutlingen, Germany

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  2. Paolo Fortina

    1. Center for Translational Medicine, Department of Medicine, Jefferson Medical College, Philadelphia

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

Part of the book series: Methods in Molecular Medicine (MIMM, volume 114)

This is a preview of subscription content, log in via an institution to check access.

Access this book

Log in via an institution
eBook USD 84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 169.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 109.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access

Licence this eBook for your library

Institutional subscriptions

Table of contents (15 protocols)

  1. Front Matter

    Pages i-xiv
    Download chapter PDF

  2. Noncontact Laser Microdissection and Pressure Catapulting

    • Yilmaz Niyaz, Monika Stich, Bernd Sägmüller, Renate Burgemeister, Gabriele Friedemann, Ulrich Sauer et al.
    Pages 1-24

  3. Applications of the Universal DNA Microarray in Molecular Medicine

    • Reyna Favis, Norman P. Gerry, Yu-Wei Cheng, Francis Barany
    Pages 25-58

  4. Sensitive Detection of SARS Coronavirus RNA by a Novel Asymmetric Multiplex Nested RT-PCR Amplification Coupled With Oligonucleotide Microarray Hybridization

    • Zhi-wei Zhang, Yi-ming Zhou, Yan Zhang, Yong Guo, Sheng-ce Tao, Ze Li et al.
    Pages 59-78

  5. Genotyping Single-Nucleotide Polymorphisms by Minisequencing Using Tag Arrays

    • Lovisa Lovmar, Ann-Christine Syvänen
    Pages 79-92

  6. Single-Nucleotide Polymorphism and Mutation Identification by the Nanogen Microelectronic Chip Technology

    • Maurizio Ferrari, Laura Cremonesi, Pierangelo Bonini, Barbara Foglieni, Stefania Stenirri
    Pages 93-106

  7. Molecular Diagnostic Testing for Inherited Thrombophilia Using Invader®

    • Margaret A. Keller
    Pages 107-119

  8. Controlled Agitation During Hybridization

    • Achim Wixforth
    Pages 121-145

  9. Rapid Screening for 31 Mutations and Polymorphisms in the Cystic Fibrosis Transmembrane Conductance Regulator Gene by Luminex® xMAP™ Suspension Array

    • Sherry A. Dunbar, James W. Jacobson
    Pages 147-171

  10. Protein Microarray-Based Screening of Antibody Specificity

    • Rhonda Bangham, Gregory A. Michaud, Barry Schweitzer, Paul F. Predki
    Pages 173-182

  11. Multiplexed Protein Analysis Using Antibody Microarrays and Label-Based Detection

    • Brian B. Haab
    Pages 183-194

  12. Allergen Microarrays

    • Tito Bacarese-Hamilton, Julian Gray, Andrea Ardizzoni, Andrea Crisanti
    Pages 195-207

  13. Enhanced Protein Profiling Arrays for Quantitative Measurement of Protein Expression in Multiple Samples

    • Ruochun Huang, Qian Shi, Weimin Yang, Ruo-Pan Huang
    Pages 209-221

  14. Multiplexed Cytokine Sandwich Immunoassays Clinical Applications

    • Uma Prabhakar, Edward Eirikis, Bruce E. Miller, Hugh M. Davis
    Pages 223-232

  15. Validation and Quality Control of Protein Microarray-Based Analytical Methods

    • Larry J. Kricka, Stephen R. Master
    Pages 233-255

  16. Tissue Microarrays

    • Ronald Simon, Martina Mirlacher, Guido Sauter
    Pages 257-268

  17. Back Matter

    Pages 269-274
    Download chapter PDF
Back to top

Keywords

About this book

Leading academic and industrial investigators surveys the world of microarray technology, describing in step-by-step detail diverse DNA and protein assays in clinical laboratories using state-of-the-art technologies. The advanced tools and methods described are designed for mRNA expression analysis, SNP analysis, identification, and quantification of proteins, and for studies of protein-protein interactions. The protocols follow the successful Methods in Molecular Biology™ series format, each offering step-by-step laboratory instructions, an introduction outlining the principle behind the technique, lists of the necessary equipment and reagents, and tips on troubleshooting and avoiding known pitfalls.

Reviews

From the reviews:

"a volume for the specialist with a fascination for the optimal collection and analysis of large data sets in microarray format."-SGM Quarterly

"...there is no other comparable book on the market...highly recommended to anyone interested in this rapidly evolving field of technology..." - Doody's Health Science Book Review Journal

"Microarray technology has become a mainstay of biological research. … The book is divided into 15 chapters … . Overall this book offers a good read to both clinicians and researchers at the bench who wish to enter the field of microarrays. The format of the book also provides a good roadmap to graduate students wishing to translate aspects of their research to methods amenable to microarrays." (Sridar V. Chittur, Clinical Chemistry, Vol. 52 (6), June, 2006)

"Microarrays in Clinical Diagnostics … is a collection of fifteen chapters by authors from both industry and academia, surveying current applications of microarray-based technologies in diagnostics … . provides protocols in the successful style of the Methods in Molecular Biology series, with clarity and sufficient technical detail so that both novice and current microarray users are sure to benefit from this book." (Nicolas Winssinger, ChemMedChem, Issue 1, 2006)

Editors and Affiliations

  • Biochemistry Department, NMI Natural and Medical Sciences Institute at the University of Tuebingen, Reutlingen, Germany

    Thomas O. Joos

  • Center for Translational Medicine, Department of Medicine, Jefferson Medical College, Philadelphia

    Paolo Fortina

Bibliographic Information

  • Book Title: Microarrays in Clinical Diagnostics

  • Editors: Thomas O. Joos, Paolo Fortina

  • Series Title: Methods in Molecular Medicine

  • DOI: https://doi.org/10.1385/1592599230

  • Publisher: Humana Totowa, NJ

  • eBook Packages: Springer Protocols

  • Copyright Information: Humana Press 2005

  • Hardcover ISBN: 978-1-58829-394-7Published: 01 June 2005

  • Softcover ISBN: 978-1-61737-538-5Published: 10 November 2010

  • eBook ISBN: 978-1-59259-923-3Published: 02 February 2008

  • Series ISSN: 1543-1894

  • Series E-ISSN: 1940-6037

  • Edition Number: 1

  • Number of Pages: 288

  • Number of Illustrations: 95 b/w illustrations, 1 illustrations in colour

  • Topics: Pathology

Publish with us

Policies and ethics

Back to top

Search

Navigation