Principles of Molecular Pathology

1. Front Matter

   Pages i-ix

   PDF

2. Basic Concepts in Molecular Pathology

   • Anthony A. Killeen

   Pages 1-29

3. Genetic Inheritance

   • Anthony A. Killeen

   Pages 31-56

4. Mutation

   • Anthony A. Killeen

   Pages 57-88

5. Methods in Molecular Pathology

   • Anthony A. Killeen

   Pages 89-139

6. Inherited Disorders

   • Anthony A. Killeen

   Pages 141-184

7. Molecular Origins of Cancer

   • Anthony A. Killeen

   Pages 185-209

8. Familial Cancer Syndromes

   • Anthony A. Killeen

   Pages 211-237

9. Molecular Pathology of Hematological Malignancies

   • Anthony A. Killeen

   Pages 239-277

10. Pharmacogenetics

    • Anthony A. Killeen

    Pages 279-295

11. Identity Testing

    • Anthony A. Killeen

    Pages 297-308

12. Molecular Diagnoses of Human Immunodeficiency Virus and Hepatitis C Virus

    • Anthony A. Killeen

    Pages 309-325

13. Back Matter

    Pages 327-333

    PDF

Anthony Killeen, MD, PhD, offers a comprehensive yet concise introduction to molecular pathology that encompasses both applied and theoretical knowledge. Writing in a very readable style, the author reviews the basic concepts of human molecular biology, explains the principles of the most commonly used analytical methods, and discusses the molecular principles that underlie both inherited diseases and acquired genetic abnormalities that lead to cancer. Using common viral infections as examples, the book applies these molecular methods to the detection of microbial pathogens. The growing importance of pharmacogenetics and identity testing in the clinical laboratory is also highlighted.

• Molecular Diagnostics
• cancer
• diagnostics
• genetics
• molecular biology
• molecular pathology
• mutation

"...nicely summarizes a broad and rapidly growing diagnostic field...This is a useful introduction to molecular pathology for a wide variety of individuals. I'd recommened it to those seeking broad, concise (but not necessarily comprehensive), and current information in this field." -Doody's Health Sciences Book Review Journal

"...a comprehensive yet concise introduction to molecular pathology that encompasses both applied and theoretical knowledge...illuminates for every pathologist, pathology resident, physician, and medical student the ongoing molecular revolution that is now transforming pathology and the practice of laboratory medicine." -Tumori

"...this book would make a welcome and timely addition to laboratory libraries...provide(s) a great service to and an excellent reference for molecular pathologists." - Clinical Chemistry

• Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, USA

  Anthony A. Killeen

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