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Animal Models of Drug Addiction

  • Book
  • © 2011

Overview

Editors:
  1. Mary C. Olmstead

    1. , Department of Psychology, Queen's University, Kingston, Canada

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  • Provides both methodological detail and a theoretical perspective in order to appeal to a wide base of readers
  • Tackles the current major challenge of the field: translation of laboratory findings to therapeutic tools
  • Presents step-by-step, clear and precise protocols for the lab
  • Includes supplementary material: sn.pub/extras

Part of the book series: Neuromethods (NM, volume 53)

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Table of contents (17 protocols)

  1. Front Matter

    Pages i-xii
    Download chapter PDF

  2. Behavioral Paradigms

    1. Front Matter

      Pages 1-1
      Download chapter PDF

    2. Intracranial Self-Stimulation

      • Styliani Vlachou, Athina Markou
      Pages 3-56

    3. Stimulant Self-Administration

      • Leigh V. Panlilio
      Pages 57-81

    4. Opiate Self-Administration

      • Francesco Leri
      Pages 83-100

    5. Nicotine Self-Administration

      • Robert E. Sorge, Paul B. S. Clarke
      Pages 101-132

    6. Alcohol Self-Administration

      • Friedbert Weiss
      Pages 133-166

    7. Place Conditioning

      • Christopher L. Cunningham, Peter A. Groblewski, Charlene M. Voorhees
      Pages 167-189

    8. Sensitization

      • Jessica A. Loweth, Paul Vezina
      Pages 191-205

    9. Animal Models of Eating Disorders

      • Stephanie D. Hancock, Mary C. Olmstead
      Pages 207-234

  3. Modeling Stages of Drug Addiction in Animals

    1. Front Matter

      Pages 235-235
      Download chapter PDF

    2. Acquisition of Drug Self-Administration

      • Marilyn E. Carroll, Richard A. Meisch
      Pages 237-265

    3. Escalation of Drug Use

      • Serge H. Ahmed
      Pages 267-292

    4. Environmental Modulation of Drug Taking

      • Aldo Badiani, Daniele Caprioli, Arianna Testa, Maria Teresa De Luca, Michele Celentano
      Pages 293-309

    5. Craving

      • Jeffrey W. Grimm
      Pages 311-336

    6. Habit Formation and Compulsion

      • David Belin, Daina Economidou, Yann Pelloux, Barry J. Everitt
      Pages 337-378

    7. Impulsivity

      • Andrea Bari, Trevor W. Robbins, Jeffrey W. Dalley
      Pages 379-401

    8. Binge Drug Taking

      • Herbert E. Covington III, Klaus A. Miczek
      Pages 403-430

    9. Withdrawal

      • Alasdair M. Barr, Heidi N. Boyda, Ric M. Procyshyn
      Pages 431-459

    10. Relapse

      • Suzanne Erb, Franca Placenza
      Pages 461-479
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Keywords

About this book

Our understanding of addiction and how it is treated has advanced remarkably over the past decades, and much of the progress is related directly to animal research. This is true for both the behavioural aspects of drug use as well as the biological underpinnings of the disorder. In Animal Models of Drug Addiction, experts in the field provide an up-to-date review of complex behavioural paradigms that model different stages of this disorder and explain how each test is used to effectively replicate the progression of drug addiction. This detailed and practical book begins with the most common laboratory measures of addiction in animals, including intracranial self-stimulation (ICSS), drug self-administration, place conditioning, and sensitization. Later chapters describe how these paradigms are used to model the progression of drug addiction, providing insight into the clinical symptomatology of addiction from acquisition of drug use through compulsive drug taking to withdrawal and relapse. Written for the popular Neuromethods series, the contributions offer both methodological detail and a theoretical perspective, appealing to readers familiar with preclinical research on drug addiction as well as those who are newcomers to the field. Cutting-edge and authoritative, Animal Models of Drug Addiction will serve as a basis for future vital research that links the bench to the bedside in the crucial treatment of drug addiction.

Reviews

From the reviews:

“This is an up-to-date review of the various animal models that are used to help researchers … . Written for readers familiar with preclinical research in addiction, the book will be extremely useful for those who need to gain a better understanding of the research available demonstrating the neurobiology of addictions. … an invaluable reference and is a must for those who wish to comprehend the preclinical data that is the basis for our scientific understanding of addictions.” (Michael Easton, Doody’s Review Service, July, 2011)

Editors and Affiliations

  • , Department of Psychology, Queen's University, Kingston, Canada

    Mary C. Olmstead

Bibliographic Information

  • Book Title: Animal Models of Drug Addiction

  • Editors: Mary C. Olmstead

  • Series Title: Neuromethods

  • DOI: https://doi.org/10.1007/978-1-60761-934-5

  • Publisher: Humana Totowa, NJ

  • eBook Packages: Springer Protocols

  • Copyright Information: Springer Science+Business Media, LLC 2011

  • Hardcover ISBN: 978-1-60761-933-8Published: 10 December 2010

  • Softcover ISBN: 978-1-4939-5745-3Published: 23 August 2016

  • eBook ISBN: 978-1-60761-934-5Published: 02 December 2010

  • Series ISSN: 0893-2336

  • Series E-ISSN: 1940-6045

  • Edition Number: 1

  • Number of Pages: XII, 484

  • Topics: Neurosciences, Psychiatry, Animal Models

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