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Anaphylaxis and Hypersensitivity Reactions

  • Book
  • © 2011

Overview

Editors:
  1. Mariana C. Castells

    1. Harvard Medical School, Ambulatory Center, Brigham and Women’s Hospital, Chestnut Hill, USA

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  • Covers trigger identification, clinical presentations, and state-of-the-art treatment
  • Provides a clear picture of the mediators and mechanisms of anaphylaxis and hypersensitivity reactions
  • Imparts essential understanding of these emergent conditions
  • Written by leading international experts
  • Includes supplementary material: sn.pub/extras

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Table of contents (22 chapters)

  1. Front Matter

    Pages i-xiii
    Download chapter PDF

  2. Definition and Criteria for the Diagnoses of Anaphylaxis

    • Phil Lieberman
    Pages 1-12

  3. An Epidemiological Approach to Reducing the Risk of Fatal Anaphylaxis

    • Richard S. H. Pumphrey
    Pages 13-31

  4. Pathophysiology and Organ Damage in Anaphylaxis

    • Stephen F. Kemp, Richard F. Lockey
    Pages 33-46

  5. Mast Cells: Effector Cells of Anaphylaxis

    • Mindy Tsai, Stephen J. Galli
    Pages 47-68

  6. Basophils in Anaphylaxis

    • David E. Sloane, Donald MacGlashan
    Pages 69-87

  7. Protease Mediators of Anaphylaxis

    • George H. Caughey
    Pages 89-105

  8. Aspirin and NSAID Reactions: Diagnosis, Pathophysiology, and Management

    • Andrew A. White, Tanya M. Laidlaw, Katharine Woessner
    Pages 107-125

  9. IgE-Dependent and Independent Effector Mechanisms in Human and Murine Anaphylaxis

    • Fred D. Finkelman
    Pages 127-144

  10. Food-Induced Anaphylaxis

    • Kirsi M. Järvinen-Seppo, Anna Nowak-WÄ™grzyn
    Pages 145-169

  11. Antibiotic-Induced Anaphylaxis

    • Pascal Demoly, Philippe Jean Bousquet, Antonino Romano
    Pages 171-182

  12. Anaphylaxis During Radiological Procedures and in the Peri-operative Setting

    • Pascale Dewachter, David L. Hepner
    Pages 183-208

  13. Hymenoptera-Induced Hypersensitivity Reactions and Anaphylaxis

    • Mitja Kosnik, Peter Korosec
    Pages 209-222

  14. Idiopathic Anaphylaxis

    • Karen Hsu Blatman, Leslie C. Grammer
    Pages 223-234

  15. Exercise-Induced Anaphylaxis and Food-Dependent Exercise-Induced Anaphylaxis

    • Anna M. Feldweg, Albert L. Sheffer
    Pages 235-243

  16. Mastocytosis and Mast Cell Activation Syndromes Presenting as Anaphylaxis

    • Cem Akin, Dean D. Metcalfe
    Pages 245-256

  17. Anaphylaxis in Mastocytosis

    • Luis Escribano, Alberto Orfao
    Pages 257-269

  18. Flushing and Urticarial Syndromes Presenting as Anaphylaxis

    • Joseph H. Butterfield
    Pages 271-284

  19. Pharmacologic Management of Acute Anaphylaxis

    • David I. Bernstein
    Pages 285-295

  20. Drug Desensitizations in the Management of Allergy and Anaphylaxis to Chemotherapeutic Agents and Monoclonal Antibodies

    • Aleena Banerji, Patrick Brennan, Paul Hesterberg, Eyal Oren, F. Ida Hsu
    Pages 297-311
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Keywords

About this book

Despite wide recognition as a serious public health problem, anaphylaxis and hypersensitivity reactions remain under-recognized and under-diagnosed. This book fills the gaps in our understanding of the identification of triggers, recognition of clinical presentations, understanding of the natural history of these reactions, and selection of treatment strategies including those focused on cellular and molecular targets. The book provides a detailed examination of disease etiology, pathogenesis, and pathophysiology and their correlation to clinical practice. Forefront knowledge of the mediators and mechanisms of anaphylaxis is covered with an emphasis on how new discoveries shape our current and emerging therapies.

Reviews

From the reviews:

“Presents a detailed look at the current state of knowledge on anaphylaxis and hypersensitivity reactions. … achieves its objectives in a very readable fashion. The book is meant for clinicians of all types, translational researchers, and basic researchers. … useful for a graduate level course. … quite readable and one could go through the book from cover to cover without losing interest. … packed with useful information about anaphylaxis and hypersensitivity reactions. The material is presented in a clear and readable fashion by experts.” (Marion C. Cohen, Doody’s Review Service, June, 2011)

Editors and Affiliations

  • Harvard Medical School, Ambulatory Center, Brigham and Women’s Hospital, Chestnut Hill, USA

    Mariana C. Castells

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