Overview
- Editors:
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Vittorio Sgaramella
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Istituto di Tecnologie Biomediche Avanzate, Consiglio Nationale Ricerche, Segrate, Italy
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Sandro Eridani
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Istituto di Tecnologie Biomediche Avanzate, Consiglio Nationale Ricerche, Segrate, Italy
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Table of contents (13 protocols)
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- Vittorio Sgaramella, Sandro Eridani
Pages 1-13
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- Grzegorz Ira, Jacek Król, Jan Filipski
Pages 35-52
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- Gérard Roizés, Christoph Grunau, Jérôme Buard, Albertina De Sario, Jacques Puechberty
Pages 77-104
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- Alessandro Vindigni, Gulnara Abdurashidova, Arturo Falaschi
Pages 105-122
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- Fiorentina Ascenzioni, Pier Assunta Fradiani, Pierluigi Donini
Pages 123-146
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- Han N. Lim, Christine J. Farr
Pages 167-186
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- Jose I. de las Heras, Leonardo D’Aiuto, Howard Cooke
Pages 187-206
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- Yoshimi Kuroiwa, Kazuma Tomizuka, Isao Ishida
Pages 207-225
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- Diane P. Monteith, Josephine D. Leung, Anita H. Borowski, Deborah O. Co, Tünde Praznovszky, Frank R. Jirik et al.
Pages 227-242
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- Michael R. Orford, Duangporn Jamsai, Samuel McLenachan, Panayiotis A. Ioannou
Pages 243-266
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Back Matter
Pages 267-269
About this book
In 1996, we organized a workshop, inter alia, at the National Research Co- cil in Milan under the generous sponsorship of the European Science Foun- tion. On that occasion, a small group of investigators convened from many countries and presented early evidence of the possibility of assembling basic units of mammalian chromosomes into artificial constructs (or, indeed, red- ing the relevant components to more manageable dimensions and defined c- stitution). Progress in the following years has been slow but steady. Many scientists who took part in the workshop have since been engaged in active and prod- tive research. It goes to the credit of Humana Press to have realized the need for a book on artificial chromosomes that aims to provide better tools to all scientists committed to this field who are confronted with very difficult tech- cal problems. We have strived to cover in Mammalian Artificial Chromosomes: Methods and Protocols all relevant areas of artificial chromosome research, from basic genetics to daring attempts to build new tools for genetic therapy. We are of course grateful to the authors who have accepted the task of describing the technical steps and pitfalls that can be encountered in their research. Rarely has a very delicate methodology been presented with such meticulous care. We have been helped in this enterprise by the excellent librarian of the LITA Institute in Segrate, Italy, Ms. Claudia Piergigli, whom we thank warmly. Ms.