Editors:
- Includes cutting-edge methods and protocols
- Provides step-by-step detail essential for reproducible results
- Contains key notes and implementation advice from the experts
Part of the book series: Methods in Molecular Biology (MIMB, volume 2055)
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Table of contents (32 protocols)
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Front Matter
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Scientific Questions and the Status of Inhibitory Receptors for Immunotherapy
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Front Matter
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Mutational and Germline Profiling
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Front Matter
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Functional Genomic Profiling
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Front Matter
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Phenotyping of Tumor and Immune Cells
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Front Matter
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About this book
This book provides the immune oncology (IO) community with a deeper understanding of the scope of the biomarker methods to potentially improve the outcome from immunotherapy. The editors secured the input from experts in the field dedicated to translating scientific research from bench to bedside was submitted. The book provides not only details about the technical, standardization and interpretation aspects of the methods but also introduces the reader to the background information and scientific justification for selected biomarkers and assays. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Editors and Affiliations
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NIH, National Cancer Institute, Bethesda, USA
Magdalena Thurin
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Nanostring Technologies, Seattle, WA, USA, ESSA Pharma, South San Francisco, USA
Alessandra Cesano
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Refuge Biotechnologies, Menlo Park, USA
Francesco M. Marincola
Bibliographic Information
Book Title: Biomarkers for Immunotherapy of Cancer
Book Subtitle: Methods and Protocols
Editors: Magdalena Thurin, Alessandra Cesano, Francesco M. Marincola
Series Title: Methods in Molecular Biology
DOI: https://doi.org/10.1007/978-1-4939-9773-2
Publisher: Humana New York, NY
eBook Packages: Springer Protocols
Copyright Information: Springer Science+Business Media, LLC, part of Springer Nature 2020
Hardcover ISBN: 978-1-4939-9772-5Published: 10 September 2019
Softcover ISBN: 978-1-4939-9775-6Published: 10 September 2020
eBook ISBN: 978-1-4939-9773-2Published: 09 September 2019
Series ISSN: 1064-3745
Series E-ISSN: 1940-6029
Edition Number: 1
Number of Pages: XVIII, 733
Number of Illustrations: 8 b/w illustrations, 111 illustrations in colour
Topics: Cancer Research, Immunology