Editors:
- Includes cutting-edge methods and protocols
- Provides step-by-step detail essential for reproducible results
- Contains key notes and implementation advice from the experts
Part of the book series: Methods in Molecular Biology (MIMB, volume 1801)
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Table of contents (22 protocols)
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Front Matter
About this book
This volume aims to detail the advances in the field of Thyroid hormones (THs), namely T3 and T4, and their nuclear receptor TRs from a conceptual and methodological point of view. Chapters guide readers through a general introduction, TR's engineered mice, human genetics of TRs, control of the hypothalamus-pituitary-thyroid (HPT) axis, the relevance of the local THs production and metabolism and pathological consequences of TH/TR alterations. Non-mammalian models are also presented and discussed. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Authoritative and practical, Thyroid Hormone Nuclear Receptor: Methods and Protocols aims to ensure successful results in the further study of this vital field.
Editors and Affiliations
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Centre Léon Bérard, Cancer Research Center of Lyon, Lyon, France
Michelina Plateroti
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École normale supérieure de Lyon, Lyon, France
Jacques Samarut
Bibliographic Information
Book Title: Thyroid Hormone Nuclear Receptor
Book Subtitle: Methods and Protocols
Editors: Michelina Plateroti, Jacques Samarut
Series Title: Methods in Molecular Biology
DOI: https://doi.org/10.1007/978-1-4939-7902-8
Publisher: Humana New York, NY
eBook Packages: Springer Protocols
Copyright Information: Springer Science+Business Media, LLC, part of Springer Nature 2018
Hardcover ISBN: 978-1-4939-7901-1Published: 12 June 2018
Softcover ISBN: 978-1-4939-9320-8Published: 25 July 2019
eBook ISBN: 978-1-4939-7902-8Published: 11 June 2018
Series ISSN: 1064-3745
Series E-ISSN: 1940-6029
Edition Number: 1
Number of Pages: XII, 300
Number of Illustrations: 18 b/w illustrations, 30 illustrations in colour
Topics: Molecular Medicine