Overview
- Includes cutting-edge methods and protocols
- Provides step-by-step detail essential for reproducible results
- Contains key notes and implementation advice from the experts
Part of the book series: Methods in Molecular Biology (MIMB, volume 1777)
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Table of contents(27 protocols)
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Fundamental Methods for Characterizing Peptide Self-Assembly
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Methods for the Preparation of Functional Self-Assembled Peptide Biomaterials
About this book
This volume details methods and protocols on b-sheet assemblies and collagen. Divided into three parts chapters focus on expanding use of solid-state NMR as a powerful method to enhance structural understanding of self-assembled peptide materials, methods for the design, synthesis, and application of self-assembled peptide materials, and structural and mechanistic analyses of pathological amyloid systems that provide novel ways to assess function of the various possible aggregates as well to determine how the structure of these materials correlates to function/dysfunction in the biological context. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Authoritative and cutting-edge, Peptide Self-Assembly: Methods and Protocols aims to capture modern methods that span the breadth of the exciting and expanding field of peptide self-assembly.
Editors and Affiliations
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Department of Chemistry, University of Rochester, Rochester, USA
Bradley L. Nilsson
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Department of Medicinal Chemistry, Institute for Translational Neuroscience, University of Minnesota, Minneapolis, USA
Todd M. Doran
Bibliographic Information
Book Title: Peptide Self-Assembly
Book Subtitle: Methods and Protocols
Editors: Bradley L. Nilsson, Todd M. Doran
Series Title: Methods in Molecular Biology
DOI: https://doi.org/10.1007/978-1-4939-7811-3
Publisher: Humana New York, NY
eBook Packages: Springer Protocols
Copyright Information: Springer Science+Business Media, LLC, part of Springer Nature 2018
Hardcover ISBN: 978-1-4939-7809-0
Softcover ISBN: 978-1-4939-9292-8
eBook ISBN: 978-1-4939-7811-3
Series ISSN: 1064-3745
Series E-ISSN: 1940-6029
Edition Number: 1
Number of Pages: XV, 452
Number of Illustrations: 77 b/w illustrations, 53 illustrations in colour
Topics: Protein Science