Editors:
- Includes cutting-edge methods and Protocols
- Provides step-by-step detail essential for reproducibles results
- Contains key notes and implementation advice from the experts
Part of the book series: Methods in Molecular Biology (MIMB, volume 1711)
Buy it now
Buying options
Tax calculation will be finalised at checkout
Other ways to access
This is a preview of subscription content, log in via an institution to check for access.
Table of contents (17 protocols)
-
Front Matter
-
Systems Biology of the Cancer Genetic and Epigenetic Landscape
-
Front Matter
-
-
Systems Analyses of Signaling Networks in Cancer Cells
-
Front Matter
-
-
Systems Analysis of Cancer Cell Metabolism
-
Front Matter
-
-
Systems Biology of Metastasis and Tumor/Microenvironment Interactions
-
Front Matter
-
-
Modeling Drug Responses in Cancer Cells
-
Front Matter
-
About this book
This book comprises protocols describing systems biology methodologies and computational tools, offering a variety of ways to analyze different types of high-throughput cancer data. Chapters give an overview over data types available in large-scale data repositories and state-of-the-art methods used in the field of cancer systems biology.  Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Authoritative and practical, Cancer Systems Biology : Methods and Protocols aims to ensure successful results in the further study of this vital field.
The chapters "Identifying Genetic Dependencies in Cancer by Analyzing siRNA Screens in Tumor Cell Line Panels", "Perseus: A Bioinformatics Platform for Integrative Analysisof Proteomics Data in Cancer Research" and "Phosphoproteomics-based Profiling of Kinase Activities in Cancer Cells" are available open access under a CC BY 4.0 license via link.springer.com.
Editors and Affiliations
-
NNF Center for Protein Research, University of Copenhagen, Copenhagen, Denmark
Louise von Stechow
Bibliographic Information
Book Title: Cancer Systems Biology
Book Subtitle: Methods and Protocols
Editors: Louise von Stechow
Series Title: Methods in Molecular Biology
DOI: https://doi.org/10.1007/978-1-4939-7493-1
Publisher: Humana New York, NY
eBook Packages: Springer Protocols
Copyright Information: Springer Science+Business Media LLC 2018
Hardcover ISBN: 978-1-4939-7492-4Published: 18 January 2018
Softcover ISBN: 978-1-4939-8503-6Published: 04 June 2019
eBook ISBN: 978-1-4939-7493-1Published: 17 January 2018
Series ISSN: 1064-3745
Series E-ISSN: 1940-6029
Edition Number: 1
Number of Pages: XI, 402
Number of Illustrations: 10 b/w illustrations, 76 illustrations in colour
Topics: Cancer Research