Editors:
- Includes cutting-edge methods and protocols
- Provides step-by-step detail essential for reproducible results
- Contains key notes and implementation advice from the experts
Part of the book series: Methods in Molecular Biology (MIMB, volume 1633)
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Table of contents (17 protocols)
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Front Matter
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Back Matter
About this book
This volume describes up-to-date techniques used in understanding the molecular biology of acute myeloid leukemia (AML) and addressing advances in diagnosis, classification, prognostication, and therapeutic strategies to potentially impact overall patient survival. The chapters in this book cover topics such as: cytochemical staining, single-cell mass cytometry of AML and Leukemia stem/progenitor cells, microsphere-based assessment of DNA methylation for AML prognosis, a zebrafish model for evaluating the function of human leukemic gene IDH1 and its mutation, and the isolation of biologically active exosomes from plasma of patients with cancer. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Cutting-edge and practical, Acute Myeloid Leukemia: Methods and Protocols is a valuable resource for scientists and researchers to further their studies and advancements in the field of AML.
Editors and Affiliations
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Thomas Jefferson University, Sidney Kimmel Cancer Center, Philadelphia, USA
Paolo Fortina
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Department of Pathology, Anatomy and Cell Biology, Sidney Kimmel Medical College Thomas Jefferson University, Philadelphia, USA
Eric Londin
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Department of Pathology, UT Southwestern Medical Center and Children’s Medical Center, Dallas, USA
Jason Y. Park
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Department of Pathology and Laboratory Medicine, University of Pennsylvania Medical Center, Philadelphia, USA
Larry J. Kricka
Bibliographic Information
Book Title: Acute Myeloid Leukemia
Book Subtitle: Methods and Protocols
Editors: Paolo Fortina, Eric Londin, Jason Y. Park, Larry J. Kricka
Series Title: Methods in Molecular Biology
DOI: https://doi.org/10.1007/978-1-4939-7142-8
Publisher: Humana New York, NY
eBook Packages: Springer Protocols
Copyright Information: Springer Science+Business Media LLC 2017
Hardcover ISBN: 978-1-4939-7140-4Published: 23 July 2017
Softcover ISBN: 978-1-4939-8396-4Published: 08 August 2018
eBook ISBN: 978-1-4939-7142-8Published: 22 July 2017
Series ISSN: 1064-3745
Series E-ISSN: 1940-6029
Edition Number: 1
Number of Pages: XI, 278
Number of Illustrations: 3 b/w illustrations, 43 illustrations in colour
Topics: Cancer Research