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  • © 2015

Metabonomics

Methods and Protocols

  • Includes cutting-edge methods and protocols
  • Provides step-by-step detail essential for reproducible results
  • Contains key notes and implementation advice from the experts

Part of the book series: Methods in Molecular Biology (MIMB, volume 1277)

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Table of contents (17 protocols)

  1. Front Matter

    Pages i-x
  2. NMR Spectroscopy of Biofluids and Extracts

    • Gwénaëlle Le Gall
    Pages 29-36
  3. High-Resolution Magic-Angle-Spinning NMR Spectroscopy of Intact Tissue

    • Guro F. GiskeødegÃ¥rd, Maria D. Cao, Tone F. Bathen
    Pages 37-50
  4. Liquid Chromatography-Mass Spectrometry of Biofluids and Extracts

    • Xinjie Zhao, Lina Zhou, Peiyuan Yin, Guowang Xu
    Pages 61-73
  5. Sample Collection and Preparation of Biofluids and Extracts for Gas Chromatography–Mass Spectrometry

    • Abdul-Hamid M. Emwas, Zeyad A. Al-Talla, Najeh M. Kharbatia
    Pages 75-90
  6. Gas Chromatography–Mass Spectrometry of Biofluids and Extracts

    • Abdul-Hamid M. Emwas, Zeyad A. Al-Talla, Yang Yang, Najeh M. Kharbatia
    Pages 91-112
  7. Capillary Electrophoresis-Mass Spectrometry

    • Masataka Wakayama, Akiyoshi Hirayama, Tomoyoshi Soga
    Pages 113-122
  8. Preprocessing of Raw Metabonomic Data

    • Riyas Vettukattil
    Pages 123-136
  9. Combining Metabonomics and Other -omics Data

    • Mattias Rantalainen
    Pages 147-159
  10. Metabonomics and Drug Development

    • Pranov Ramana, Erwin Adams, Patrick Augustijns, Ann Van Schepdael
    Pages 195-207
  11. Metabonomics and Toxicology

    • Liang Zhao, Thomas Hartung
    Pages 209-231
  12. Metabonomics and Diagnostics

    • Lucy C. Hicks, Simon J. L. Ralphs, Horace R. T. Williams
    Pages 233-244
  13. Metabonomics and Systems Biology

    • Vicky De Preter
    Pages 245-255
  14. Back Matter

    Pages 257-259

About this book

This volume on metabonomics provides detailed information on the procedures involved in nuclear magnetic resonance (NMR) spectroscopy, gas chromatography-mass spectrometry (GS-MS), liquid chromatography-mass spectrometry (LC-MS), and capillary electrophoresis-mass spectrometry (CE-MS). Chapters focus on technologies and chemometrics, generation of metabonomics data, extraction of meaningful information from data, drug development, toxicology, diagnostics, and describing metabonomics as an essential part of systems biology. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

Editors and Affiliations

  • Department of Gastroenterology, Medical Section, Herlev Hospital, University of Copenhagen, Copenhagen, Denmark

    Jacob T. Bjerrum

Bibliographic Information

  • Book Title: Metabonomics

  • Book Subtitle: Methods and Protocols

  • Editors: Jacob T. Bjerrum

  • Series Title: Methods in Molecular Biology

  • DOI: https://doi.org/10.1007/978-1-4939-2377-9

  • Publisher: Humana New York, NY

  • eBook Packages: Springer Protocols

  • Copyright Information: Springer Science+Business Media New York 2015

  • Hardcover ISBN: 978-1-4939-2376-2Published: 13 February 2015

  • Softcover ISBN: 978-1-4939-4837-6Published: 05 October 2016

  • eBook ISBN: 978-1-4939-2377-9Published: 12 February 2015

  • Series ISSN: 1064-3745

  • Series E-ISSN: 1940-6029

  • Edition Number: 1

  • Number of Pages: X, 259

  • Number of Illustrations: 26 b/w illustrations, 48 illustrations in colour

  • Topics: Bioinformatics, Systems Biology

Buy it now

Buying options

eBook USD 84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 119.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 109.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access