Overview
- Reviews the current understanding of how helminth infections impact the ability to control unrelated infections
- Covers new evidence about helminth infections controlling allergy and immune mechanisms
- Examines helminth infections protecting against various auto-immune diseases
- Includes supplementary material: sn.pub/extras
Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 828)
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Table of contents (6 chapters)
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Front Matter
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Back Matter
Keywords
About this book
Helminth infections are common, cause considerable pathology, and alter a host’s immune profile. This can have important consequences not only on the host’s ability to control a helminth infection, but also on their ability to control unrelated infections. In endemic areas, understanding how helminth infection influences the outcome of common infectious diseases and changes the efficacy of childhood vaccination programs is an important public health question.
This book reviews how host immunity to helminths alters our ability to respond to the major pathogens that exist in helminth endemic regions. Current understanding of how helminths alter important but relatively neglected contributors to the host’s anti-helminth immune responses are addressed, namely host antibody responses and how maternal infection may alter a child’s immune development. These are discussed in relation to the control of helminth infection and unrelated infections. Also covered are how helminth infections alter the host’s ability to control TB, HIV and malarial infections along with neglected bacterial infections, such as cholera, and how endemic helminth infections are likely to alter our ability to respond to life-saving vaccination strategies.
Editors and Affiliations
About the editor
William Horsnell is an immunologist at the University of Cape Town, South Africa. His research interests center on how parasitic helminth infections alter host immunity and the ability to control both the helminth and unrelated diseases.
Bibliographic Information
Book Title: How Helminths Alter Immunity to Infection
Editors: William Horsnell
Series Title: Advances in Experimental Medicine and Biology
DOI: https://doi.org/10.1007/978-1-4939-1489-0
Publisher: Springer New York, NY
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature 2014
Hardcover ISBN: 978-1-4939-1488-3Published: 25 September 2014
Softcover ISBN: 978-1-4939-5419-3Published: 10 September 2016
eBook ISBN: 978-1-4939-1489-0Published: 24 September 2014
Series ISSN: 0065-2598
Series E-ISSN: 2214-8019
Edition Number: 1
Number of Pages: X, 152
Number of Illustrations: 6 illustrations in colour
Topics: Immunology, Infectious Diseases, Parasitology