Editors:
- Characterizes the anatomy and physiology of the lymphovascular system
- Describes the mechanisms of metastasis
- Outlines the prognostic factors and clinical outcome of metastasis
- Provides readers with an understanding of immune responses of draining lymph nodes against cancer
- Explains the rationale of adopting molecular therapeutics against growth factor receptors, apoptotic factors, signaling pathways and angiogenesis
Part of the book series: Cancer Treatment and Research (CTAR, volume 135)
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Table of contents (21 chapters)
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Front Matter
About this book
Sentinel lymph node (SLN) procedures have opened a window of opportunity for the study of micrometastasis. In eighty percent (80%) of metastasis there lies an orderly pattern of progression via the lymphatic network, while 20% of the time systemic metastasis occurs, bypassing the lymphatic system. During the past two decades, significant progress has been achieved in understanding the anatomical, functional, cellular and molecular aspects of the lymphovascular system and the metastasis process.
· Molecular imaging advances help to localize early cancers more precisely.
· Current status of the immune responses in the draining lymph nodes against cancer is summarized.
· New paradigms of early cancer growth, proliferation, overcoming apoptosis are exploited in the development of anticancer treatment.
In this book, basic scientists and clinicians exchange ideas so that laboratory findings can be applied to clinical dilemmas, and clinical problems can be targeted for research in the laboratory.
Editors and Affiliations
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University of California San Francisco and UCSF Comprehensive Cancer Center at Mount Zion, San Francisco, USA
Stanley P. L. Leong
Bibliographic Information
Book Title: Cancer Metastasis and the Lymphovascular System:
Book Subtitle: Basis for Rational Therapy
Editors: Stanley P. L. Leong
Series Title: Cancer Treatment and Research
DOI: https://doi.org/10.1007/978-0-387-69219-7
Publisher: Springer New York, NY
eBook Packages: Medicine, Medicine (R0)
Copyright Information: Springer-Verlag US 2007
Hardcover ISBN: 978-0-387-69218-0Published: 06 August 2007
Softcover ISBN: 978-1-4899-9102-7Published: 21 September 2014
eBook ISBN: 978-0-387-69219-7Published: 05 September 2007
Series ISSN: 0927-3042
Series E-ISSN: 2509-8497
Edition Number: 1
Number of Pages: XVII, 309
Topics: Oncology, Hematology, Internal Medicine