Overview
- Editors:
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Alan A. Boulton
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University of Saskatchewan, Saskatoon, Canada
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Glen B. Baker
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University of Alberta, Edmonton, Canada
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Roger F. Butterworth
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University of Montreal, Montreal, Canada
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Table of contents (11 protocols)
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Front Matter
Pages i-xviii
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- Karen A. Seta, R. Christian Crumrine, Tim S. Whittingham, W. David Lust, David W. McCandless
Pages 1-50
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- Gary E. Gibson, Hsueh-Meei Huang
Pages 51-93
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- Maryse Héroux, Roger F. Butterworth
Pages 95-131
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- David W. McCandless, Ross B. FineSmith
Pages 133-151
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- Marc S. Abel, David W. McCandless
Pages 153-168
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- David W. McCandless, Marc S. Abel
Pages 169-182
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- Andres T. Blei, Reed Omarg, Roger F. Butterworth
Pages 183-222
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- M. G. Murphy, S. C. Digout, J. F. S. Crocker
Pages 223-257
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- Krishnamurti Dakshinamurti, S. K. Sharma, K. J. Lal
Pages 299-327
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Back Matter
Pages 357-373
About this book
to the Animal Models Volumes This and several other volumes in the Neuromethods series will describe a number of animal models of neuropsychiatric disorders. Because of increasing public concern over the ethical treatment of animals in research, we felt it incumbent upon us to include this general preface to these volumes in order to indicate why we think further - search using animals is necessary and why animal models of psychiatric disorders, in particular, are so important. We recognize that animals should only be used when suitable alternatives are not available. We think it self-e- dent, however, that humans can only be experimented upon in severely proscribed circumstances and alternative pro- dures using cell or tissue culture are inadequate in any models requiring assessments of behavioral change or of complex in vivo processes. However, when the distress, discomfort, or pain to the animals outweighs the anticipated gains for human welfare, then the research is not ethical and should not be carried out. It is imperative that each individual researcher examine his/her own research from a critical moral standpoint - fore engaging in it, taking into consideration the animals’ welfare as well as the anticipated gains. Furthermore, once a decision to proceed with research is made, it is the researcher’s responsibility to ensure that the animals’ w- fare is of prime concern in terms of appropriate housing, feeding, and maximum reduction of any uncomfortable or distressing effects of the experimental conditions, and that these conditions undergo frequent formalized monitoring.
Reviews
These books go out of their way to be helpful. Most chapters introduce the animal models against the background of the human (i.e., clinical) context and conclude with a brief summary. Detailed experimental protocols and useful tabulations abound. Descriptions are exhaustive.-Trends in Neurosciences
Editors and Affiliations
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University of Saskatchewan, Saskatoon, Canada
Alan A. Boulton
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University of Alberta, Edmonton, Canada
Glen B. Baker
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University of Montreal, Montreal, Canada
Roger F. Butterworth