Overview
- Editors:
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Nathan Back
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Department of Biochemical Pharmacology, School of Pharmacy, State University of New York, Buffalo, USA
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Luciano Martini
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Institute of Pharmacology, University of Milan, Milan, Italy
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Rodolfo Paoletti
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Institute of Pharmacology, University of Cagliari, Cagliari, Italy
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Table of contents (76 papers)
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Peptide and Protein Chemistry
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- Miguel A. Ondetti, John T. Sheehan, M. Bodanszky
Pages 18-31
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- L. Bernardi, G. Bosisio, R. de Castiglione, O. Goffredo
Pages 32-34
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Posterior Pituitary Hormones
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- J. Rudinger, V. Pliška, I. Rychlík, F. Šorm
Pages 66-72
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- Seymour M. Glick, Mary Wheeler, Avir Kagan, Perianna Kumaresan
Pages 93-100
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- Roderich Walter, Irving L. Schwartz
Pages 101-104
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Hypothalamic Neurohumoral Principles
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- L. Desclin, J. Flament-Durand
Pages 105-111
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- S. M. McCann, S. Watanabe, D. B. Crighton, D. Beddow, A. P. S. Dhariwal
Pages 112-122
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- H. Gregory, A. L. Walpole, H. M. Charlton, G. W. Harris, May Reed
Pages 123-127
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- M. Jutisz, A. Berault, M. P. de la Llosa
Pages 138-147
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About this book
It can be concluded (under the specific experimental procedures em ployed) that:- 1) HCG labelled with 1 - 2 atoms of radioactive iodine did not differ sig nificantly from the unlabelled hormone; 2) The ovary alone exhibited a capacity to affix specifically HCG; 3) The amount of radioactive material in the ovary was directly proport ional to the quantity of labelled HCG injected; 4) When the HCG present in the circulation is bound to an antiserum to HCG, the antigen-antibody complex is not concentrated by the ovary; 5) Circulating labelled HCG decreased to 50% within 30 minutes following a single intravenous injection; 6) There are four different phases of ovarian uptake of HCG, namely: the first phase, when there is only an inflow from the circulation and stor age mainly in the follicular envelopes; the second phase, when there is a greater inflow than outflow; the third phase, when the inflow is equal to the outflow; and the fourth period, when the outflow is bigger than the in flow. REFERENCES 1. Lunenfeld, B. and Eshkol, A. Vitamins and Hormones (1967) 25:165 2. Eshkol, A. In: Recent Research on Gonadotropbio Hormones, eds. E. T. Bell andJ. A. Loraine, Edinburgh, Livingstone (1967), p. 202. 3. Eshkol, A. and Lunenfeld, B. Proc. Tel-Hashomer Hosp. (1967) 6:4. ACKNOWLEOOMEN'IS This work was supported in part by a grant from the Population Council, N. Y. , U. S. A. andbyGrantNo.
Editors and Affiliations
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Department of Biochemical Pharmacology, School of Pharmacy, State University of New York, Buffalo, USA
Nathan Back
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Institute of Pharmacology, University of Milan, Milan, Italy
Luciano Martini
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Institute of Pharmacology, University of Cagliari, Cagliari, Italy
Rodolfo Paoletti