Recent Advances in Prostaglandin, Thromboxane, and Leukotriene Research

1. Front Matter

   Pages i-xiv

   PDF

2. Some Recent Advances in Leukotriene Research

   • Bengt Samuelsson

   Pages 1-7

3. Practical Aspects of Prostaglandin E1 before and after Solid Organ Transplantation

   • H. Müller, A. Wasler, B. Petutschnigg, T. Allmayer, B. Grasser, G. Prenner et al.

   Pages 9-12

4. Prostaglandins in Liver Transplantation

   • Robert M. Merion

   Pages 13-18

5. Prostaglandins in Heart Transplantation

   • F. Iberer, A. Wasler, B. Petutschnigg, H. Müller, T. Allmayer, B. Grasser et al.

   Pages 19-22

6. Eicosanoids in Periodontal Diseases: Potential for Systemic Involvement

   • Suzanne M. Damaré, Steve Wells, Steven Offenbacher

   Pages 23-35

7. Mitogen-Activated Protein Kinases and Endothelial Prostacyclin Secretion

   • John H. Grose, Luc Caron, Marcel Lebel

   Pages 37-40

8. Crosstalk Between Elevation of [Ca2+]i, Reactive Oxygen Species Generation and Phospholipase A2 Stimulation in a Human Keratinocyte Cell Line

   • Rachel Goldman, Sandra Moshonov, Xiaomei Chen, Alexander Berchansky, Gerhard Fürstenberger, Uriel Zor

   Pages 41-45

9. Cloning, Tissue-Specific Expression and Regulation of the Bovine Thromboxane A2 Receptor

   • Stephanie Muck, Karsten Schrör

   Pages 47-50

10. Weak Inhibitors of Cyclooxygenases May Exert Their Antinociceptive Effect by Modulation of Transcription Factors

    • Nicole Scheuren, Holger Bang, Tino Münster, Kay Brune, Andreas Pahl

    Pages 51-54

11. New Group of Lipid Mediators Containing ω-Hydroxyarachadonic Acid (20-HETE)

    • Kaiyun Mao, K. Kishta Reddy, J. R. Falck, John C. McGiff, Michael Balazy

    Pages 55-59

12. Biosynthesis of Novel Divinyl Ether Oxylipins by Enzyme From Garlic (Allium sativum L.) Bulbs

    • Alexander N. Grechkin, Mats Hamberg

    Pages 61-64

13. Catalytic and Spectroscopic Properties of Linoleate Diol Synthase of the Fungus Gaümannomyces graminis

    • Ernst H. Oliw, Chao Su

    Pages 65-68

14. Avenoleic Acid: A New Oxylipin from Oat Seeds

    • Mats Hamberg

    Pages 69-72

15. Discovery of Novel Cannabinoid Receptor Ligands from Diverse Marine Organisms

    • Ken Soderstrom, Thomas F. Murray, Hye-Dong Yoo, Sharon Ketchum, Ken Milligan, William Gerwick et al.

    Pages 73-77

16. Accumulation of Platelets as a Key Mechanism of Human Erection. A Scintigraphic Study in Patients with Erectile Dysfunction Receiving Intracavernous Injection of PGE1, Papaverine/Phentolamine

    • Margarida Rodrigues, Susanne Granegger, John O’Grady, Helmut Sinzinger, Walter Stackl

    Pages 79-82

17. Can Self-Injection Therapy Cure Impotence?

    • Ira D. Sharlip

    Pages 83-86

18. Cytokine Levels in Five Different Fluid Compartments During Amniotic Fluid Infection and Labour

    • Gundula Hebisch

    Pages 87-90

19. Characterization of A-93178, an Iminoxy-Quinoline

    • R. L. Bell, R. R. Harris, J. B. Bouska, K. I. Hulkower, J. Moore, P. Bhatia et al.

    Pages 91-94

20. Transcellular Synthesis of CYS-LT: From Isolated Cells to Complex Organ System

    • Angelo Sala, Giuseppe Rossoni, Ferruccio Berti, Reiner Müller-Peddinghaus, Giancarlo Folco

    Pages 95-98

The International Symposium on Prostaglandins and Related Compounds, first held in Vienna 1972, revisited the city after 24 years for the 10TH Symposium. For the many re­ searchers working in this multi-disciplinary field it was an opportunity to exchange their ex­ periences and share new data with colleagues from all around the world. This scientific exchange was largely encouraged by the unseasonably cold and rainy weather. For the first time, there was quite a large attendance from the former Communist countries. Eugene Garfield prepared a key note address delivered during the meeting (The Sci­ entist 1996, 12) reviewing the contribution of the Nobel Laureates U.S. von Euler, l.R. Vane, S.K. Bergstrom, and B.I. Samuelsson, discussing the relevance of the more than 40,000 pa­ pers in this area published since 1991. Overall, there is still a rapidly growing interest, and in particular a great variety of clinical applications of this family of compounds which were dis­ cussed in detail during the meeting. Beside the lectures there were 19 workshops covering nearly all the topics of key in­ terest. All the speakers were invited to prepare a manuscript which has resulted in the volume now in your hands. Special thanks to Dr. Patrick Wong and the new publisher of this series who helped to publish the proceedings in the usual quality and reasonable period of time. Looking forward to seeing all of you again in Florence in 1999, hopefully with much more sun.

• Lipid
• clinical application
• endothelium
• enzymes
• tissue
• transcription

• Wilhelm Auerswald Atherosclerosis Research Group Vienna, University of Vienna, Vienna, Austria

  Helmut Sinzinger

• Karolinska Institutet, Stockholm, Sweden

  Bengt Samuelsson

• The William Harvey Research Institute, London, England

  John R. Vane

• University of Milan, Milan, Italy

  Rodolfo Paoletti

• Georgetown University Medical Center, USA

  Peter Ramwell

• University of Medicine and Dentistry of New Jersey, Stratford, USA

  Patrick Y.-K. Wong

Sir John Vane is the Director General at the William Harvey Research Institute, an independent charitable foundation within Queen Mary and Westfield College of the University of London, UK.
Sir John Vane shared the Nobel Prize in Physiology or Medicine in 1982 for his discoveries of the mechanism of action of aspirin and of prostacyclin, as well as his work on other prostanoids.

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