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Diet and Cancer

Markers, Prevention, and Treatment

  • Book
  • © 1994

Overview

Editors:
  1. Maryce M. Jacobs

    1. American Institute for Cancer Research, USA

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Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 375)

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Table of contents (48 chapters)

  1. Front Matter

    Pages i-xvii
    Download chapter PDF

  2. Vitamin-Regulated Retinoblastoma Tumor Suppressor Gene Expression in Leukemic Cells

    1. Vitamin-Regulated Retinoblastoma Tumor Suppressor Gene Expression in Leukemic Cells

      • Andrew Yen, Tracy French, Karen Russell, Susi Varvayanis, Mary Forbes
      Pages 1-18

  3. Retinoic Acid Suppresses Human Papillomavirus Type 16 (HPV16)-Mediated Transformation of Human Keratinocytes and Inhibits the Expression of the HPV16 Oncogenes

    1. Retinoic Acid Suppresses Human Papillomavirus Type 16 (HPV16)-Mediated Transformation of Human Keratinocytes and Inhibits the Expression of the HPV16 Oncogenes

      • Kim E. Creek, G. Ronald Jenkins, Mohammad A. Khan, Ayse Batova, John R. Hodam, William H. Tolleson et al.
      Pages 19-35

  4. Interactions Between Retinoic Acid and Protein Kinase C in Induction of Melanoma Differentiation

    1. Interactions Between Retinoic Acid and Protein Kinase C in Induction of Melanoma Differentiation

      • Richard M. Niles
      Pages 37-57

  5. Racial and Ethnic Issues in Diet and Cancer Epidemiology

    1. Racial and Ethnic Issues in Diet and Cancer Epidemiology

      • Shiriki Kumanyika
      Pages 59-70

  6. Dietary Modulation of Oxidative DNA Damage

    1. Dietary Modulation of Oxidative DNA Damage

      • Zora Djuric, Silvana Martino, Lance K. Heilbrun, Ronald W. Hart
      Pages 71-83

  7. Carbohydrate Tumor Marker: Basis for a Simple Test for Colorectal Cancer

    1. Carbohydrate Tumor Marker: Basis for a Simple Test for Colorectal Cancer

      • Abulkalam M. Shamsuddin, Kosaku Sakamoto
      Pages 85-99

  8. Chemical and Mutagenic Specificities of Polycyclic Aromatic Hydrocarbon Carcinogens

    1. Chemical and Mutagenic Specificities of Polycyclic Aromatic Hydrocarbon Carcinogens

      • Anthony Dipple, Kimmo Peltonen, S. Chau Cheng, Helen Ross, C. Anita H. Bigger
      Pages 101-112

  9. Inhibition of Tumorigenesis by Chemicals from Garlic and Tea

    1. Inhibition of Tumorigenesis by Chemicals from Garlic and Tea

      • Chung S. Yang, Zhi-Yuan Wang, Jun-Yan Hong
      Pages 113-122

  10. Cancer Chemoprevention by Green Tea Components

    1. Cancer Chemoprevention by Green Tea Components

      • Hasan Mukhtar, Santosh K. Katiyar, Rajesh Agarwal
      Pages 123-134

  11. Potential Role of Dietary Isoflavones in the Prevention of Cancer

    1. Potential Role of Dietary Isoflavones in the Prevention of Cancer

      • Stephen Barnes, Greg Peterson, Clinton Grubbs, Ken Setchell
      Pages 135-147

  12. Carcinogen-DNA and Protein Adducts as Intermediate Biomarkers for Human Chemoprotection Trials

    1. Carcinogen-DNA and Protein Adducts as Intermediate Biomarkers for Human Chemoprotection Trials

      • John D. Groopman, Bill D. Roebuck, Thomas W. Kensler
      Pages 149-160

  13. Cytokines, Iron Homeostasis, and Cancer

    1. Cytokines, Iron Homeostasis, and Cancer

      • Frank M. Torti, Suzy V. Torti
      Pages 161-170

  14. Evidence for Nutrient Modulation of Tumor Phenotype: Impact of Tyrosine and Phenylalanine Restriction

    1. Evidence for Nutrient Modulation of Tumor Phenotype: Impact of Tyrosine and Phenylalanine Restriction

      • Catherine A. Elstad, Gary G. Meadows, Cheryl J. Aslakson, Jean R. Starkey
      Pages 171-183

  15. Possible Role of Neuropeptide Y in Experimental Cancer Anorexia

    1. Possible Role of Neuropeptide Y in Experimental Cancer Anorexia

      • William T. Chance, Ambikaipakan Balasubramaniam, Sulaiman Sheriff, Josef E. Fischer
      Pages 185-201

  16. Metabolic Alterations and Lactate Overproduction in Insulin-Resistant States

    1. Metabolic Alterations and Lactate Overproduction in Insulin-Resistant States

      • Mario Digirolamo
      Pages 203-210
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Keywords

About this book

The American Institute for Cancer Research (AICR) sponsored its third annual confer­ ence on nutrition and cancer. The theme was "Diet and Cancer: Markers, Prevention, and Treatment. " The conference was held October 29-30, 1992 at the Ritz Carlton Hotel in McLean, Virginia. This proceedings contains chapters from the platform presentations and abstracts from the poster presentations. Several chapters address each of four session topics: Retinoids as Differentiation Agents in Cancer Therapy, Biological Markers of Cancer Risk, Chemoprevention of Cancer by Non-Nutrients in Foods, and Nutritional Problems and Support in the Treatment of Cancer. The first three chapters discuss in detail different mechanisms by which retinoids influence differentiation and provide evidence to support their use in cancer therapy. In vivo and in vitro studies show the effects of retinoic acid (RA) on tumorigenicity and cellu­ lar/molecular events. A synopsis of data showing the involvement of the retinoblastoma (RB) gene in HL-60 cell differentiation induced by RA and 1,2S-dihydroxy vitamin D3 (VD) is presented. In SCID (severe combined immunodeficiency) mice injected with HL-60 3 human leukemia cells and gavaged daily with RA, the number of tumor sites and number of mice with tumors are reduced. All trans-RA induces myeloid differentiation in HL-60 cells. Similarly, VD3 induces HL-60 monocytic differentiation. In both cases an early down regulation of retinoblastoma (RB) gene expression precedes the differentiation.

Editors and Affiliations

  • American Institute for Cancer Research, USA

    Maryce M. Jacobs

Bibliographic Information

  • Book Title: Diet and Cancer

  • Book Subtitle: Markers, Prevention, and Treatment

  • Editors: Maryce M. Jacobs

  • Series Title: Advances in Experimental Medicine and Biology

  • DOI: https://doi.org/10.1007/978-1-4899-0939-8

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature 1994

  • Hardcover ISBN: 978-0-306-44723-5Published: 31 May 1994

  • Softcover ISBN: 978-1-4899-0941-1Published: 06 June 2013

  • eBook ISBN: 978-1-4899-0939-8Published: 22 November 2013

  • Series ISSN: 0065-2598

  • Series E-ISSN: 2214-8019

  • Edition Number: 1

  • Number of Pages: XVIII, 256

  • Topics: Oncology, Nutrition, Biochemistry, general

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