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Steroid Hormone Receptor Systems

  • Book
  • © 1979

Overview

Editors:
  1. Wendell W. Leavitt

    1. Worcester Foundation for Experimental Biology, Shrewsbury, USA

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  2. James H. Clark

    1. Baylor College of Medicine, Houston, USA

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    You can also search for this editor in PubMed   Google Scholar

Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 117)

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Table of contents (25 chapters)

  1. Front Matter

    Pages i-ix
    Download chapter PDF

  2. The Immunoendocrinology of Estrophilin

    • E. V. Jensen, G. L. Greene, L. E. Closs, E. R. DeSombre
    Pages 1-16

  3. Nuclear Binding of the Estrogen Receptor: Heterogeneity of Sites and Uterotropic Response

    • James H. Clark, Barry Markaverich, Susan Upchurch, HÃ¥kan Eriksson, James W. Hardin
    Pages 17-46

  4. The Specific Binding of Estradiol to the Nuclear Matrix

    • Evelyn R. Barrack, Edward F. Hawkins, Donald S. Coffey
    Pages 47-70

  5. Heterogeneity of Nuclear Glucocorticoid Receptor Interactions

    • John A. Cidlowski, Allan Munck
    Pages 71-93

  6. Estrogen Control of Progesterone Receptor Induction in Human Breast Cancer: Role of Nuclear Estrogen Receptor

    • Kathryn B. Horwitz, William L. McGuire
    Pages 95-110

  7. Estrogen and Antiestrogen Action: Studies in Reproductive Target Tissues and Tumors

    • Benita S. Katzenellenbogen, Ten-lin S. Tsai, Tochiro Tatee, John A. Katzenellenbogen
    Pages 111-132

  8. Inhibition of Cell Division and Stimulation of Progesterone Receptor Synthesis in Rat Oestrogen Target Tissues by Non-Steroidal Antioestrogens

    • V. C. Jordan, C. J. Dix, G. Prestwich
    Pages 133-155

  9. Steroid Hormone Regulation of Uterine Peroxidase Activity

    • Eugene R. DeSombre, C. Richard Lyttle
    Pages 157-171

  10. Progesterone Suppression of the Estradiol Receptor in the Reproductive Tract of Macaques, Cats, and Hamsters

    • Robert M. Brenner, Neal B. West, Reid L. Norman, Bruce A. Sandow, Harold G. Verhage
    Pages 173-196

  11. Regulation and Function of Estrogen and Progesterone Receptor Systems

    • Wendell W. Leavitt, Tong J. Chen, Rawden W. Evans
    Pages 197-222

  12. Effects of Progestins on the Progesterone Receptor in Guinea Pig Uterus

    • Judith Saffran, Bonnie K. Loeser, Lee E. Faber
    Pages 223-239

  13. The Use of Medroxyprogesterone Acetate to Study Progestin Receptors in Immature, Pregnant, and Adult Rabbit Uterus

    • P. D. Feil, C. W. Bardin
    Pages 241-254

  14. Circannual Rhythms in Progesterone Receptor Levels and Functions

    • T. C. Spelsberg, P. A. Boyd, F. Halberg
    Pages 255-268

  15. In Vivo Metabolism and Binding of 6α-Methylprogesterone; A Progestin with Anti-Androgenic and Synandrogenic Activities

    • Terry R. Brown, Leslie P. Bullock, C. Wayne Bardin
    Pages 269-280

  16. Factors Regulating the Androgenic Action of Progestins in Mouse Kidney

    • Leslie P. Bullock, C. Wayne Bardin
    Pages 281-295

  17. The Role of Ligand-Binding as a Determinant of the Structure and Activation of the Estrogen Receptor

    • A. C. Notides, B. M. Weichman, N. Lerner, W. de Boer
    Pages 297-307

  18. Structural Relationships between the Chick Oviduct Progesterone Receptor A and B Proteins

    • Wayne V. Vedeckis, W. T. Schrader, Bert W. O’Malley
    Pages 309-327

  19. Characterization of the Avian Progesterone Receptor Through the Use of Inhibitors

    • David Toft, P. Elaine Roberts, Hideo Nishigori, Virinder K. Moudgil
    Pages 329-341

  20. Glucocorticoid Receptor Inactivation and Activation by Phosphorylation Mechanisms

    • William B. Pratt, Julianne J. Sando, Carl J. Nielsen
    Pages 343-356
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Keywords

About this book

The papers in this volume were presented at the Symposium on Steroid Hormone Receptor Systems held October 18-20, 1978, at the Worcester Foundation for Experimental Biology, Shrewsbury, Mass. The meeting was organized to review, discuss, and disseminate new knowledge about the regulation and function of the receptor proteins which mediate estrogen, progestin, glucocorticoid, and androgen action. The symposium brought together leading scientists whose interests span the spectrum of biological organization. On this occasion, Drs. Elwood V. Jensen and Etienne E. Baulieu were honored as recipients of the Tenth Annual Gregory Pincus l1emorial Award for their pioneering studies of steroid hormone receptors. The material covered in this book focuses on the molecular mechanisms which control receptor site availability and function. The topics discussed include recent work on receptor antibodies, antiestrogen action, receptor heterogeneity, nuclear binding and processing of receptor, receptor activation and inactivation mechan­ isms, interactions between receptor systems, influence of biological rhythms, membrane binding sites, and the evolution of steroid-bind­ ing proteins. Although studies on steroid receptors have led to the development of new approaches for cancer therapy and contraception, much remains to be discovered in this rapidly expanding field. Hope­ fully, this book will provide added impetus to the quest for a full understanding of steroid receptor systems by drawing attention to the unresolved questions yet to be answered. Hhile the book is intended primarily for those interested in hormone action, it should be of value to a more general audience including cell, molecular, and developmental biologists.

Editors and Affiliations

  • Worcester Foundation for Experimental Biology, Shrewsbury, USA

    Wendell W. Leavitt

  • Baylor College of Medicine, Houston, USA

    James H. Clark

Bibliographic Information

  • Book Title: Steroid Hormone Receptor Systems

  • Editors: Wendell W. Leavitt, James H. Clark

  • Series Title: Advances in Experimental Medicine and Biology

  • DOI: https://doi.org/10.1007/978-1-4757-6589-2

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature 1979

  • Softcover ISBN: 978-1-4757-6591-5Published: 14 February 2013

  • eBook ISBN: 978-1-4757-6589-2Published: 09 March 2013

  • Series ISSN: 0065-2598

  • Series E-ISSN: 2214-8019

  • Edition Number: 1

  • Number of Pages: IX, 489

  • Number of Illustrations: 255 b/w illustrations

  • Topics: Tree Biology

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