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Vascular Endothelium

Receptors and Transduction Mechanisms

  • Book
  • © 1989

Overview

Editors:
  1. John D. Catravas

    1. Medical College of Georgia, Augusta, USA

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  2. C. Norman Gillis

    1. Yale University School of Medicine, New Haven, USA

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    You can also search for this editor in PubMed   Google Scholar

  3. Una S. Ryan

    1. University of Miami School of Medicine, Miami, USA

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Part of the book series: NATO Science Series B: (NSSB, volume 308)

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Table of contents (24 chapters)

  1. Front Matter

    Pages i-xii
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  3. Receptors

    1. Front Matter

      Pages 67-67
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    2. Purine Receptors on Endothelial Cells

      • John L. Gordon
      Pages 69-75

    3. Muscarinic Receptors on Endothelial Cells

      • John D. Catravas, Alain B. Legrand, Una S. Ryan, Robert S. Aronstam
      Pages 77-88

    4. Comparison between Paf-Acether Receptors on Intact Washed Human Platelets and Human Endothelial Cells in Culture

      • Ruth Korth, M. Hirafuji, J. Bidault, B. Canton, F. Russo-Marie, J. Benveniste
      Pages 89-98

    5. Prostaglandins as Transducers of Proliferation Signals in Microvascular Endothelial Cells and the Pharmacological Control of Angiogenesis

      • Anthony C. Allison, W. Joseph Kowalski
      Pages 99-110

    6. The Role of Basement Membrane in Angiogenesis

      • Michael E. Maragoudakis
      Pages 111-120

    7. The Role of Cytokines in the Symbiotic Relationship between Leukocytes and Vascular Endothelia

      • Alberto Mantovani, Elisabetta Dejana
      Pages 121-127

    8. Response of Vascular Cells to Herpes Simplex Virus Infection

      • Nicholas A. Kefalides, Zahra Ziaie
      Pages 129-139

    9. Receptors for Extracellular Matrix Proteins in Endothelial Cells

      • Elisabetta Dejana, G. Conforti, A. Zanetti, M. G. Lampugnani, P. C. Marchisio
      Pages 141-147

    10. Cellular Distribution and Heterogeneity of Endothelial Cell Adhesion Receptors

      • Jan A. van Mourik, Jacques C. Giltay, Albert E. G. Kr. von dem Borne
      Pages 149-154
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Keywords

About this book

Beyond their obvious role of a barrier between blood and tissue, vascular endothelial cells are now firmly established as active and essential participants in a host of crucial physiological and pathophysiological functions. Probably the two most important factors responsible for promoting the current knowledge of endothelial functions are 1) observations in the late sixties-early seventies that many non-ventilatory properties of the lung could be attributed to the pulmonary endothelium and 2) the establishment, in the early and mid-seventies of procedures for routine culture of vascular endothelial cells. Many of these endothelial functions require the presence of receptors on the surface of the plasma membrane. There is now evidence for the existence among others of muscarinic, a-and /3-adrenergic, purine, insulin, histamine, bradykinin, lipoprotein, thrombin, paf, fibronectin, vitronectin, interleukin and albumin receptors. For some of these ligands, there is evidence only for the existence of endothelial binding sites. Traditionally, agonist binding must elicit a response for the binding site to be considered a receptor and, in some cases, the nature of the response resulting from the interaction of a substance with the endothelium remains unclear. It is beyond the scope of this introduction to even enumerate the various endothelial homeostatic processes. This monograph contains the proceedings of the Advanced Studies Institute on "Vascular Endothelium: Receptors and Transduction Mechanisms" held in Porto Carras, Greece from June 18-29, 1988.

Editors and Affiliations

  • Medical College of Georgia, Augusta, USA

    John D. Catravas

  • Yale University School of Medicine, New Haven, USA

    C. Norman Gillis

  • University of Miami School of Medicine, Miami, USA

    Una S. Ryan

Bibliographic Information

  • Book Title: Vascular Endothelium

  • Book Subtitle: Receptors and Transduction Mechanisms

  • Editors: John D. Catravas, C. Norman Gillis, Una S. Ryan

  • Series Title: NATO Science Series B:

  • DOI: https://doi.org/10.1007/978-1-4684-8532-5

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: Plenum Press, New York 1989

  • Softcover ISBN: 978-1-4684-8534-9Published: 22 May 2013

  • eBook ISBN: 978-1-4684-8532-5Published: 29 June 2013

  • Series ISSN: 0258-1221

  • Edition Number: 1

  • Number of Pages: XII, 308

  • Number of Illustrations: 65 b/w illustrations

  • Topics: Biochemistry, general

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