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Drugs Affecting Leukotrienes and Other Eicosanoid Pathways

  • Book
  • © 1985

Overview

Editors:
  1. B. Samuelsson

    1. Karolinska Institute, Stockholm, Sweden

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  2. F. Berti

    1. University of Milan, Milan, Italy

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  3. G. C. Folco

    1. University of Milan, Milan, Italy

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  4. G. P. Velo

    1. University of Verona, Verona, Italy

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Part of the book series: NATO Science Series A: (NSSA, volume 95)

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Table of contents (29 chapters)

  1. Front Matter

    Pages i-x
    Download chapter PDF

  2. Introduction

    • Bengt Samuelsson
    Pages 1-3

  3. Measurement of Thromboxane Production in Vivo: Metabolic and Analytical Aspects

    • E. Granström, P. Westlund, M. Kumlin, A. Nordenström
    Pages 5-17

  4. High Pressure Liquid Chromatography-125J-RIA, A Sensitive and Specific Prostaglandin Assay

    • T. Mourits-Andersen, R. Jensen, J. Dyerberg
    Pages 19-30

  5. Enzyme Immunoassays of Icosanoids Using Acetylcholinesterase

    • P. Pradelles, J. Maclouf, J. Grassi
    Pages 31-38

  6. Syntheses and Biological Effects of Leukotrienes and Analogs

    • Bernd Spur, Attilio Crea, Wilfried Peters
    Pages 39-53

  7. Pharmacologic Modulation of Leukotriene Biosynthesis by Incorporation of Alternative Unsaturated Fatty Acids (20:5 and 22:6)

    • Robert A. Lewis, Tak H. Lee, K. Frank Austen
    Pages 55-71

  8. Studies with Inhibitors of Leukotriene Biosynthesis with Special Reference to Piriprost (U-60,257)

    • Michael K. Bach
    Pages 73-86

  9. Pulmonary and Vascular Effects of Leukotrienes: Involement in Asthma and Inflation

    • Per Hedqvist, Sven-Erik Dahlén
    Pages 87-101

  10. Modulation of the Release of Leukotrienes and Prostaglandins and of their Functional Effects in Human and Guinea-Pig Lung Parenchyma

    • G. C. Folco, L. Sautebin, G. Rossoni, T. Viganò, M. T. Crivellari, G. Galli et al.
    Pages 103-120

  11. Comparative Effects of Leukotrienes in Respiratory Tissue of Various Species

    • Marwa N. Samhoun, Priscilla J. Piper, Neil C. Barnes
    Pages 121-129

  12. The Effects of Low-Dose Aspirin and Selective Inhibitors of Thromboxane-Synthase on Eicosanoid Production in Man

    • Carlo Patrono, Paola Filabozzi, Paola Patrignani
    Pages 131-140

  13. Manipulation of Pro- and Antiaggregating Prostaglandins: New Antithrombotic Strategies

    • H. Deckmyn, P. Gresele, J. Arnout, J. Vermylen
    Pages 141-147

  14. Flavonoids — Lipoxygenases — Platelet Aggregation

    • R. J. Gryglewski, J. Robak, J. SwiÄ™s
    Pages 149-166

  15. Transformation of 15-Hydroperoxyeicosapentaenoic Acid Into Mono-and Dihydroxyeicosapentaenoic Acids by Human Platelets

    • Bing Lam, Ewa Marcinkiewicz, Patrick Y-K Wong
    Pages 167-180

  16. Metabolism of Arachidonic Acid by 12- and 15-Lipoxygenases in Human Platelets and Polymorphonuclear Leukocytes

    • Patrick Y-K Wong, Par Westlund, Mats Hamberg, Elisabeth Granstrom, Patricia H-W Chao, Bengt Samuelsson
    Pages 181-195

  17. Epoxidation of Arachidonic Acid and Prostacyclin in the Kidney

    • Patrick Y-K. Wong, John C. McGiff, Michal Schwartzman, F. F. Sun
    Pages 197-210

  18. The Effect of 9α-Fluorohydrocortisone on the Urinary Excretion of 6-KETO-PGF1α in Man

    • P. Minuz, G. Capuzzo, M. Degan, C. Lechi, G. Covi, G. P. Velo et al.
    Pages 211-220

  19. Prostacyclin in Therapy of Vascular Disease

    • R. J. Gryglewski, A. Szczeklik
    Pages 221-238

  20. LTC4 Induces Hyperreactivity of the Isolated Vascular Tissue to Histamine, Serotonin and Norepinephrine

    • L. Daffonchio, C. Omini, G. Brunelli, F. Berti
    Pages 239-247
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Keywords

Editors and Affiliations

  • Karolinska Institute, Stockholm, Sweden

    B. Samuelsson

  • University of Milan, Milan, Italy

    F. Berti, G. C. Folco

  • University of Verona, Verona, Italy

    G. P. Velo

Bibliographic Information

  • Book Title: Drugs Affecting Leukotrienes and Other Eicosanoid Pathways

  • Editors: B. Samuelsson, F. Berti, G. C. Folco, G. P. Velo

  • Series Title: NATO Science Series A:

  • DOI: https://doi.org/10.1007/978-1-4684-7841-9

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: Plenum Press, New York 1985

  • Softcover ISBN: 978-1-4684-7843-3Published: 06 May 2012

  • eBook ISBN: 978-1-4684-7841-9Published: 06 December 2012

  • Edition Number: 1

  • Number of Pages: X, 394

  • Number of Illustrations: 76 b/w illustrations

  • Topics: Pharmacology/Toxicology

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