Immunobiology of Proteins and Peptides VI

1. Front Matter

   Pages i-xiii

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2. Structure and Function in Recombinant HIV-1 gp120 and Speculation about the Disulfide Bonding in the gp120 Homologs of HIV-2 and SIV

   • Timothy Gregory, James Hoxie, Colin Watanabe, Michael Spellman

   Pages 1-14

3. The Lentivirus Regulatory Proteins REV and REX are Site Specific RNA Binding Proteins

   • G. King Farrington, Paul Lynch, Amy Jensen, Ernst Böhnlein, Reed Doten, Theodore Maione et al.

   Pages 15-22

4. HIV-1 Neutralizing Antibody and Approaches to the Envelope Diversity Problem

   • Thomas J. Matthews, Alphonse J. Langlois, Stephano Butto, Dani Bolognesi, Kashi Javaherian

   Pages 23-26

5. Molecular Mechanisms in the Pathogenesis of AIDS-Associated Kaposi’s Sarcoma

   • Barbara Ensoli, Giovanni Barillari, Luigi Buonaguro, Robert C. Gallo

   Pages 27-38

6. Structure-Function Analysis of the HIV Glycoprotein

   • John W. Dubay, Hae-ja Shin, Jian-yun Dong, Susan Roberts, Eric Hunter

   Pages 39-46

7. Maternal Antibody Epitope Mapping in Mother-to-Child Transmission of HIV

   • Paolo Rossi, Viviana Moschese, Anita de Rossi, Britta Wahren, Marianne Jansson, Valter Lombardi et al.

   Pages 47-52

8. Immunogenicity of Synthetic Peptides Corresponding to Various Epitopes of the Human Immunodeficiency Virus Envelope Protein

   • Habib Zaghouani, Brenda Hall, Himanshu Shah, Constantin Bona

   Pages 53-62

9. Common Sequence in HIV-1 GP41 and HLA Class II Beta Chains can Generate Crossreactive Autoantibodies with Immunosuppressive Potential Early in the Course of HIV-1 Infection

   • Robert Blackburn, Mario Clerici, Dean Mann, Daniel R. Lucey, James Goedert, Basil Golding et al.

   Pages 63-69

10. Isolation and Characterization of the Neutralizable Epitope of Simian Retrovirus-1 (SRV-1) and of the Cell Receptor for the Virus

    • Eli Benjamini, Jose V. Torres, Linda L. Werner, Arthur Malley

    Pages 71-77

11. Complexes and Conjugates of cis-Pt for Immunotargeted Chemotherapy

    • Ruth Arnon, Bilha Schechter, Meir Wilchek

    Pages 79-90

12. Radiolabeled Antibody Therapy of Human B Cell Lymphomas

    • Oliver W. Press, Janet F. Eary, Christopher C. Badger, Paul J. Martin, Frederick R. Appelbaum, Wil B. Nelp et al.

    Pages 91-96

13. Activation of Prodrugs by Antibody-Enzyme Conjugates

    • Peter D. Senter, Philip M. Wallace, Hakan P. Svensson, David E. Kerr, Ingegerd Hellstrom, Karl Erik Hellstrom

    Pages 97-105

14. Cancer Imaging and Therapy with Radiolabeled Antibodies

    • David M. Goldenberg

    Pages 107-117

15. Genetic Approaches to a Vaccine for Pertussis

    • Luciano Nencioni, Mariagrazia Pizza, Gianfranco Volpini, Audino Podda, Rino Rappuoli

    Pages 119-127

16. Strategies for Type-Specific Glycoconjugate Vaccines of Streptococcus pneumoniae

    • Beth Arndt, Massimo Porro

    Pages 129-148

17. Immunoprophylaxis of Otitis Media

    • G. Scott Giebink

    Pages 149-158

18. Protection against Streptococcal Pharyngeal Colonization with Vaccines Composed of M Protein Conserved Regions

    • V. A. Fischetti, D. E. Bessen, O. Schneewind, D. E. Hruby

    Pages 159-167

19. Oral Delivery of Antigens in Live Bacterial Vectors

    • Robert N. Brey, Garvin S. Bixler, James P. Fulginiti, Deborah A. Dilts, Marta I. J. Sabara

    Pages 169-184

20. Augmentation by Interleukins of the Antibody Response to a Conjugate Vaccine against Haemophilus influenzae B

    • Garvin S. Bixler Jr., Subramonia Pillai

    Pages 185-190

The articles in this volume represent papers delivered by invited speakers at the 6th International Symposium on the Immunobiology of Proteins and Peptides. In addition, a few of the abstracts submitted by participants were scheduled for minisymposia and some of the authors, whose presentations were judged by the Scientific Council to be of high quality, were invited to submit papers for publication in this volume. This symposium was established in 1976 for the purpose of bringing together, once every two or three years, active investigators in the forefront of contemporary immunology, to present their findings and discuss t heir significance in the light of current concepts and to identify important new directions of investigation. The founding of the symposium was stimulated by the achievement of major breakthroughs in the understanding of the immune recognition of proteins and peptides. We believed that these breakthroughs will lead to the creation of a new generation of peptide reagents which should have enormous potential in biological, therapeutic and basic applications. This anticipated explosion has in fact since occurred and many applications of these pep tides are now being realized.

• biology
• immunobiology
• immunology
• protein
• proteins

• Baylor College of Medicine, Houston, USA

  M. Zouhair Atassi

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