Neuroreceptor Mechanisms in Brain

1. Front Matter

   Pages i-xii

   PDF

2. Effect of Neuropeptides on Classic Types of Neurotransmission in the Rat Central Nervous System

   • Shozo Kito, Rie Miyoshi

   Pages 1-11

3. Solubilization and Characterization of Substance P Receptors in the Central Nervous System

   • Tomio Segawa, Yoshihiro Nakata

   Pages 13-25

4. Evidence for Cardiovascular Roles of Tachykinin Peptides in the Brain of the Rat

   • Hiro-o Kamiya, Yukio Takano, Akira Nagashima

   Pages 27-37

5. Functions of a Co-Transmitter, Calcitonin Gene-Related Peptide, on the Neuromuscular Junction

   • Shuji Uchida, Kenji Takami, Hideyuki Kobayashi, Kazuya Hashimoto, Naoko Matsumoto

   Pages 39-50

6. Pharmacological Characterization of Sigma Binding Sites in Guinea Pig Brain Membranes

   • E. W. Karbon, S. J. Enna

   Pages 51-59

7. Transmitter-Activated Ion Channels as the Target of Chemical Agents

   • Toshio Narahashi

   Pages 61-73

8. Chemical Kinetic Investigations of the Channel-Opening Process of Neurotransmitter Receptors

   • Norio Matsubara, Andrew P. Billington, Hou Chang Chen, Anthony P. Guzikowski, Katherine W. Johnson, Doraiswamy Ramesh et al.

   Pages 75-82

9. Primary Structure and Functional Expression of the Inositol 1,4,5-Trisphosphate Receptor, P400

   • Katsuhiko Mikoshiba, Teiichi Furuichi, Nobuaki Maeda, Shingo Yoshikawa, Atsushi Miyawaki, Michio Niinobe et al.

   Pages 83-95

10. Inositol 1,4,5-Trisphosphate Activates Ca2+ Channels in the Plasma Membranes of Rat Brain Nerve Terminals

    • M. Satoh, H. Ueda, S. Tamura, Y. Yoshihara, N. Fukushima

    Pages 97-110

11. Formation of Inositol Polyphosphates in Cultured Adrenal Chromaffin Cells

    • Nobuyuki Sasakawa, Toshio Nakaki, Ryuichi Kato

    Pages 111-123

12. Effects of Oxygen Depletion on Phosphoinositide Breakdown in Rat Brain Slices

    • Haruaki Ninomiya, Takashi Taniguchi, Motohatsu Fujiwara

    Pages 125-139

13. Expression of G-Protein α-Subunit cDNA

    • Toshihide Nukada

    Pages 141-149

14. Serotonin Receptor Subtypes in Brain: Ligand Binding Properties and Coupling with G Proteins

    • Yasuyuki Nomura, Yoshihisa Kitamura, Michihisa Tohda, Shin-ichi Imai, Toshiaki Katada, Michio Ui

    Pages 151-164

15. A Cerebral Endogenous Factor Regulates the Activity of the Serotonergic Receptors Modulating the Neuronal Release of Acetylcholine

    • Gilles Fillion, Pascal Barone, Isabelle Cloëz, Marie-Paule Fillion, Catherine Harel, Olivier Massot et al.

    Pages 165-176

16. Serotonin Receptor Heterogeneity and the Role of Potassium Channels in Neuronal Excitability

    • J. S. Kelly, P. Larkman, N. J. Penington, D. G. Rainnie, H. McAllister-Williams, J. Hodgkiss

    Pages 177-191

17. Modulatory Actions of Norepinephrine on Neural Circuits

    • D. J. Woodward, H. C. Moises, B. D. Waterhouse, H. H. Yeh, J. E. Cheun

    Pages 193-208

18. Genetic Analysis of the β-Adrenergic Receptor

    • Catherine D. Strader, Richard A. F. Dixon

    Pages 209-220

19. Reversal of Nigrostriatal-Lesion-Induced Receptor Alterations by Grafting of Fetal Mesencephalic Dopaminergic Neurons

    • James K. Wamsley, Ted M. Dawson, Valina L. Dawson, Mary A. Hunt, Lisa J. Fisher, Fred H. Gage

    Pages 221-235

20. Octopamine: An Endogenous Blocker of Dopamine D-1 Receptors

    • Juei-Tang Cheng, Jui-Ting Tsai

    Pages 237-240

The Third International Symposium on Neurotransmitter Receptors was held in Hiroshima at a time when the entire field of neurotransmitter receptors in the brain is progressing at an unprecedented pace. The sym­ posium also marked my retirement as Professor and Chairman of the Third Department of Internal Medicine, Hiroshima University School of Medicine, and a new beginning as a Professor of the University of the Air. The symposium was remarkably successful, and there were enthusiastic responses from scientists allover the world, proving that the meeting was timely. The selected papers contained in this volume constitute a state­ of-the-art survey of the most advanced aspects of neurotransmitter recep­ tor mechanisms in the brain. lowe thanks for the great success of the symposium to Prof. Richard Olsen of UCLA, Prof. Tomio Segawa of Hiroshima University, Prof. Kinya Kuriyama of Kyoto Prefectural University of Medicine, and Prof. Masaya Tohyama of Osaka University. I express my sincere gratitude to many friends for making this publication possible. I especially thank Dr. Rie Miyoshi, whose devoted efforts as secretary-general were vital to the success of the symposium. Dr. Miyoshi is currently an instructor in the Department of Pharmacology at Tokyo Women's Medical College. I would also like to acknowledge the excellent secretarial work of Misses Ritsuko Sato and Yuko Wakita.

• Amino acid
• Calcium
• Epilepsie
• Glutamat
• Nervous System
• adenosine
• dopamine
• gene expression
• neurons
• neuropeptides
• primary structure

• Division of Health Sciences, University of the Air, Chiba 260, Japan

  Shozo Kito

• Department of Pharmacology Institute of Pharmaceutical Sciences, Hiroshima University School of Medicine, Minami-ku Hiroshima 734, Japan

  Tomio Segawa

• Department of Pharmacology Center for Health Sciences, University of California-Los Angeles School of Medicine, Los Angeles, USA

  Richard W. Olsen

Policies and ethics