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Red Cell Metabolism and Function

Proceedings of the First International Conference on Red Cell Metabolism and Function, held at the University of Michigan, Ann Arbor, October 1–3, 1969

  • Conference proceedings
  • © 1970

Overview

Editors:
  1. George J. Brewer

    1. Departments of Human Genetics and Medicine (Simpson Memorial Institute), University of Michigan, Ann Arbor, USA

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Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 6)

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Table of contents (22 papers)

  1. Front Matter

    Pages i-xix
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  2. Relationship Between Red Cell Metabolism and Function

    1. Front Matter

      Pages 1-1
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  3. Metabolic Control Mechanisms in the Red Cell

    1. Front Matter

      Pages 115-115
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  4. Interaction of the Cardiac, Pulmonary, and Erythrocyte Systems in Respiratory Homeostasis

    1. Front Matter

      Pages 175-175
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    2. R. Grover, Chairman

      1. The Respiratory Function of the Blood
        • Giles F. Filley
        Pages 177-190
      2. Systemic Oxygen Transport
        • Robert F. Grover, John V. Weil
        Pages 191-201
      3. Adaptation to Hypoxia
        • C. Lenfant, J. D. Torrance, R. Woodson, C. A. Finch
        Pages 203-212
      4. Adaptation of the Red Blood Cell to Muscular Exercise
        • John A. Faulkner, George J. Brewer, John W. Eaton
        Pages 213-227
      5. A Comparison of Mechanisms of Oxygen Transport Among Several Mammalian Species
        • James Metcalfe, Dharam S. Dhindsa
        Pages 229-241
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Keywords

About this book

In the last six years, a remarkable series of stUdies have demonstrated an intimate relationship between red cell metabolism and the function of the cell as an organ of gas transport. First came the demonstration of binding of organic phosphocompounds of the red cell to hemoglobin; this was followed by studies that demonstrated modification of hemoglobin oxygen affinity by such binding. At present we are in an exhilirating phase of accrual of data showing that the levels of these phosphorylated inter­ mediates can be rapidly altered in the red cell to modulate hemo­ globin function. At one time it was said that the red cell was an inert bag full of hemoglobin. Now we know not only that the cell has an active metabolism crucial to its viability, but that this metabolism is just as crucial to the whole organism in the proper adjustment of oxygen transport. On October first, second and third, 1969, red cell biochemists, general biochemists, geneticists, cardio-pulmonary physiologists, exercise physiologists, experts in blood storage, and represen­ tatives from many other disciplines met in the Towsley Center for Continuing Medical Education at the University of Michigan, Ann Arbor, to present recent findings and discuss developments in this new interdisciplinary field. The meeting was dedicated to Dr. Alfred Chanutin, Professor Emeritus of the University of Virginia, to honor his retirement in 1967 and in recognition of his great contributions to the studies outlined in the first paragraph of this preface.

Editors and Affiliations

  • Departments of Human Genetics and Medicine (Simpson Memorial Institute), University of Michigan, Ann Arbor, USA

    George J. Brewer

Bibliographic Information

  • Book Title: Red Cell Metabolism and Function

  • Book Subtitle: Proceedings of the First International Conference on Red Cell Metabolism and Function, held at the University of Michigan, Ann Arbor, October 1–3, 1969

  • Editors: George J. Brewer

  • Series Title: Advances in Experimental Medicine and Biology

  • DOI: https://doi.org/10.1007/978-1-4684-3195-7

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature 1970

  • Softcover ISBN: 978-1-4684-3197-1Published: 24 April 2012

  • eBook ISBN: 978-1-4684-3195-7Published: 09 March 2013

  • Series ISSN: 0065-2598

  • Series E-ISSN: 2214-8019

  • Edition Number: 1

  • Number of Pages: XIX, 390

  • Topics: Hematology, Human Physiology

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