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Neurobiology of Cerebrospinal Fluid 1

  • Book
  • © 1980

Overview

Editors:
  1. James H. Wood

    1. Division of Neurosurgery, University of Pennsylvania School of Medicine, Philadelphia, USA
      Pediatric Oncology Branch, National Cancer Institute National National Institutes of Health, Bethesda, USA

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Table of contents (49 chapters)

  1. Front Matter

    Pages i-xxvii
    Download chapter PDF

  2. Physiology, Pharmacology, and Dynamics of Cerebrospinal Fluid

    • James H. Wood
    Pages 1-16

  3. Role of Cyclic AMP in Cerebrospinal Fluid Production

    • Arthur M. Feldman, Mel H. Epstein, Saul W. Brusilow
    Pages 17-27

  4. Chemical Alterations of Cerebrospinal Fluid Acting on Respiratory and Circulatory Control Systems

    • Hans H. Loeschcke
    Pages 29-40

  5. Neurochemical Aspects of Blood-Brain-Cerebrospinal Fluid Barriers

    • Robert W. P. Cutler
    Pages 41-51

  6. Sites of Origin and Cerebrospinal Fluid Concentration Gradients

    • James H. Wood
    Pages 53-62

  7. Daily Fluctuations in Catecholamines, Monoamine Metabolites, Cyclic AMP, and γ-Aminobutyric Acid

    • Mark J. Perlow, C. Raymond Lake
    Pages 63-69

  8. Technical Aspects of Clinical and Experimental Cerebrospinal Fluid Investigations

    • James H. Wood
    Pages 71-96

  9. Cerebrospinal Fluid Amine Metabolites and the Probenecid Test

    • Michael H. Ebert, Ronald Kartzinel, Rex W. Cowdry, Frederick K. Goodwin
    Pages 97-112

  10. Extracellular Cyclic Nucleotide Metabolism in the Human Central Nervous System

    • Benjamin Rix Brooks, James H. Wood, Maria Diaz, Carol Czerwinski, Leon P. Georges, Jonas Sode et al.
    Pages 113-139

  11. Norepinephrine in Cerebrospinal Fluid

    • Michael G. Ziegler, C. Raymond Lake, James H. Wood, Michael H. Ebert
    Pages 141-152

  12. Huntington’s Disease

    • Ian J. Butler, William E. Seifert, S. J. Enna
    Pages 153-160

  13. Cerebrospinal Fluid Noradrenergic and Behavioral Alterations Associated with Stimulation and Atrophy of the Caudate Nucleus

    • James H. Wood, Michael G. Ziegler, C. Raymond Lake, Ira Shoulson, Benjamin Rix Brooks
    Pages 161-169

  14. Evaluation of Cerebrospinal Fluid γ-Aminobutyric Acid Content in Neurological and Psychiatric Disorders

    • Theodore A. Hare, N. V. Bala Manyam, Bruce S. Glaeser
    Pages 171-187

  15. Cerebrospinal Fluid γ-Aminobutyric Acid Correlation with Cerebrospinal Fluid and Blood Constituents and Alterations in Neurological Disorders

    • S. J. Enna, Michael G. Ziegler, C. Raymond Lake, James H. Wood, Benjamin Rix Brooks, Ian J. Butler
    Pages 189-196

  16. Cerebrospinal Fluid Studies in Parkinson’s DiseaseNorepinephrine and γ-Aminobutyric Acid Concentrations

    • Paul F. Teychenne, C. Raymond Lake, Michael G. Ziegler
    Pages 197-206

  17. Neurochemical Alterations in Parkinson’s Disease

    • Thomas N. Chase
    Pages 207-218

  18. Cerebrospinal Fluid Monoamine Metabolites in Neurological Disorders of Childhood

    • Bennett A. Shaywitz, Donald J. Cohen, Malcolm B. Bowers Jr.
    Pages 219-236

  19. Seizure-Induced Metabolic Alterations in Human Cerebrospinal Fluid

    • Benjamin Rix Brooks
    Pages 237-257

  20. Neurotransmitter, Metabolite, and Cyclic Nucleotide Alterations in Cerebrospinal Fluid of Seizure Patients

    • James H. Wood, Benjamin Rix Brooks
    Pages 259-278
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Keywords

About this book

Physiologic compartmentalization effectively isolates the central nervous system from the rest of the body. This isolation not only provides protection of its delicate function from aberrant peripheral influences but also impedes its diagnostic evaluation. Cerebro­ spinal fluid (CSF) bathes the brain and spinal cord, is in dynamic equilibrium with its extracellular fluid, and tends to reflect the state of health and activity of the central nervous system. CSF examination is the most direct and popular method of assessing the central chemical and cellular environment in the living patient or mammal. The purpose of this multidisciplined reference text is to provide the sophisticated knowledge of CSF physiology and pathology necessary for the meaningful interpretation of data obtained by various types of CSF analysis. The methodology for reliable CSF collection, storage, preparation, and analysis is discussed with respect to individual, somatotropic, chronologic, endorcinologic, pharmacologic, and possible artifactual var­ iations in CSF composition. These essential aspects, which ensure the validity of CSF data, are presented to aid the investigator in clinical and experimental protocol formu­ lation and in elimination of possible sources of error.

Editors and Affiliations

  • Division of Neurosurgery, University of Pennsylvania School of Medicine, Philadelphia, USA

    James H. Wood

  • Pediatric Oncology Branch, National Cancer Institute National National Institutes of Health, Bethesda, USA

    James H. Wood

Bibliographic Information

  • Book Title: Neurobiology of Cerebrospinal Fluid 1

  • Editors: James H. Wood

  • DOI: https://doi.org/10.1007/978-1-4684-1039-6

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: Plenum Press, New York 1980

  • Softcover ISBN: 978-1-4684-1041-9Published: 19 March 2012

  • eBook ISBN: 978-1-4684-1039-6Published: 29 June 2013

  • Edition Number: 1

  • Number of Pages: XXVIII, 768

  • Topics: Neurobiology, Science, Humanities and Social Sciences, multidisciplinary

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