Overview
- Introduces emerging approaches of biophysics for vascular regeneration
- Describes advanced technologies for basic and translation research in vascular biology
- Presents methodology of implementation of advance technologies in stem cells based vascular studies
- Brings together experts' work and views from various disciplines including engineers, biophysics, biologists, and clinicians
- Includes supplementary material: sn.pub/extras
Part of the book series: Biological and Medical Physics, Biomedical Engineering (BIOMEDICAL)
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Table of contents (10 chapters)
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Front Matter
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Back Matter
Keywords
About this book
Because of their ability to differentiate and develop into functional vasculature, stem cells hold tremendous promise for therapeutic applications. However, the scientific understanding and the ability to engineer these cellular systems is still in its early stages, and must advance significantly for the therapeutic potential of stem cells to be realized. Stem cell differentiation and function are exquisitely tuned by their microenvironment. This book will provide a unique perspective of how different aspect of the vasculature microenvironment regulates differentiation and assembly. Recent efforts to exploits modern engineering techniques to study and manipulate various biophysical cues will be described including: oxygen tension during adult and embryonic vasculogenesis (Semenza and Zandstra), extracellular matrix during tube morphogenesis and angiogenesis (Wirtz, Davis, Ingber), surface topography and modification (Chen and Gerecht), shear stress and cyclic strain effect on vascular assembly and maturation (Vunjak-Novakovic and Niklason), and three dimensional space for angio-andvasculogensis (Ferreria and Fischbach).
Editors and Affiliations
Bibliographic Information
Book Title: Biophysical Regulation of Vascular Differentiation and Assembly
Editors: Sharon Gerecht
Series Title: Biological and Medical Physics, Biomedical Engineering
DOI: https://doi.org/10.1007/978-1-4419-7835-6
Publisher: Springer New York, NY
eBook Packages: Physics and Astronomy, Physics and Astronomy (R0)
Copyright Information: Springer Science+Business Media, LLC 2011
Softcover ISBN: 978-1-4614-2793-3Published: 24 February 2013
eBook ISBN: 978-1-4419-7835-6Published: 06 January 2011
Series ISSN: 1618-7210
Series E-ISSN: 2197-5647
Edition Number: 1
Number of Pages: XIV, 254
Topics: Biological and Medical Physics, Biophysics, Biomedical Engineering and Bioengineering, Stem Cells